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carbonylcyanide 4-trifluoromethoxyphenylhydrazone (carbonylcyanide p-trifluoromethoxyphenylhydrazone)

Also Known As:

carbonylcyanide p-trifluoromethoxyphenylhydrazone; COCN 3FMeOPhHZN

Networked: 5 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrazines: 379
  - Hydrazones: 500
    - Carbonyl Cyanide m-Chlorophenyl Hydrazone: 187
      - carbonylcyanide 4-trifluoromethoxyphenylhydrazone: 5
- Nitriles: 227
  - Carbonyl Cyanide m-Chlorophenyl Hydrazone: 187
    - carbonylcyanide 4-trifluoromethoxyphenylhydrazone: 5

Experts

1.	Cai, Xiangyu: 1 article (05/2014)
2.	Chen, Guo: 1 article (05/2014)
3.	Chen, Linbo: 1 article (05/2014)
4.	Chen, Quan: 1 article (05/2014)
5.	Chen, Yanfang: 1 article (05/2014)
6.	Duan, Liangwei: 1 article (05/2014)
7.	Feng, Du: 1 article (05/2014)
8.	Fu, Changying: 1 article (05/2014)
9.	Han, Zhe: 1 article (05/2014)
10.	Huang, Li: 1 article (05/2014)

Related Diseases

1.	Hypoxia (Hypoxemia) 04/01/1987 - "Measurement of the sequestered Ca2+ pool of mitochondria by selective release with the protonophore, carbonylcyanide-p-trifluoromethoxyphenylhydrazone (FCCP), and quantitation with the metallochromic indicator, arsenazo III, showed that anoxia caused a marked decrease in mitochondrial Ca2+. This loss could, in part, be due to decreased electrophoretic uptake resulting from a 20% decrease in the magnitude of the mitochondrial transmembranal potential. " 05/08/2014 - "Here, we identify that the mitochondrially localized PGAM5 phosphatase interacts with and dephosphorylates FUNDC1 at serine 13 (Ser-13) upon hypoxia or carbonylcyanide p-trifluoromethoxyphenylhydrazone (FCCP) treatment. "
2.	Poisoning 11/01/1984 - "Apart from the symptoms of poisoning which the fluorinated arylalkylsulphonamides share with the classical protonphore and uncoupler of oxidative phosphorylation, carbonylcyanide p-trifluoromethoxyphenylhydrazone (FCCP), the direct correlation between the lipophilic weak acid properties of these chemicals and their biological activity suggests that permeation of the inner mitochondrial membrane could be the initial step in the molecular mechanism of their biological activity. "
3.	Paralysis (Palsy) 06/01/1985 - "Carbonylcyanide-p-trifluoromethoxyphenylhydrazone and carbonylcyanide-m-chlorophenylhydrazone, which are uncouplers of oxidative phosphorylation, induce a spastic paralysis of the fluke; this is rapid at high concentrations (1 X 10(-4) and 1 X 10(-5) M). "
4.	Muscle Spasticity (Spastic) 06/01/1985 - "Carbonylcyanide-p-trifluoromethoxyphenylhydrazone and carbonylcyanide-m-chlorophenylhydrazone, which are uncouplers of oxidative phosphorylation, induce a spastic paralysis of the fluke; this is rapid at high concentrations (1 X 10(-4) and 1 X 10(-5) M). "
5.	Dehydration (Water Stress) 05/01/1980 - "4. The dehydration was inhibited by 2 mM azide, 1 mM arsenate, 1 mM hydroxylamine, 20 micro M dinitrophenol or 10 micro M carbonylcyanide p-trifluoromethoxyphenylhydrazone. "

Related Drugs and Biologics

1.	Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone (FCCP)
2.	Indicators and Reagents (Reagents)
3.	Arsenazo III
4.	Hydroxylamine (Hydroxylamine Hydrochloride)
5.	Serine (L-Serine)
6.	Phosphoric Monoester Hydrolases (Phosphatases)
7.	Azides
8.	Acids
9.	arsenic acid (arsenate)