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polyaconitylated human serum albumin

potential drug carrier system

Also Known As:

Aco-HSA

Networked: 3 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Albumins: 31532
    - Serum Albumin: 9893
      - Human Serum Albumin: 2275
        polyaconitylated human serum albumin: 3
  - Blood Proteins: 12459
    - Serum Albumin: 9893
      - Human Serum Albumin: 2275
        polyaconitylated human serum albumin: 3
Organic Chemicals: 133
- Carboxylic Acids: 973
  - Acyclic Acids
    - Tricarboxylic Acids: 423
      - Aconitic Acid: 42
        polyaconitylated human serum albumin: 3

Related Diseases

1.	Acquired Immunodeficiency Syndrome (AIDS) 01/01/1996 - "The present pharmacokinetic and toxicologic data of Suc-HSA and Aco-HSA show that both compounds are interesting preparations for studies in SIV infected monkeys and AIDS patients."
2.	Human Influenza (Influenza) 04/04/1997 - "Aco-HSA and Suc-HSA markedly inhibited the rates and extents of fusion of fluorescently labeled virosomes bearing influenza HA, with target membranes derived from erythrocytes. "
3.	Infections 01/01/1997 - "Negatively charged albumins (NCAs, with the prototypes succinylated human serum albumin (Suc-HSA) and aconitylated human serum albumin (Aco-HSA)), modified proteins with a potent anti-human immunodeficiency virus type 1 (anti-HIV-1) activity in vitro, were studied for their pharmacokinetic behaviour in mice and their in vivo anti-HIV-1 efficacy in an HIV-1 infection model in mice. "

Related Drugs and Biologics

1.	Suc-HSA
2.	Virosomes
3.	Proteins (Proteins, Gene)
4.	Albumins
5.	Human Serum Albumin