neurotrypsin

12/01/2011 - "Our results define neurotrypsin- and age-dependent sarcopenia as the common final outcome of 2 etiologically distinct entities."
12/01/2011 - "Using histological and functional analyses of neurotrypsin-overexpressing and neurotrypsin-deficient mice, we found that overexpression of neurotrypsin in motoneurons installed the full sarcopenia phenotype in young adult mice. "
12/01/2011 - "Studies of neurotrypsin-deficient and agrin-overexpressing mice revealed that old-age sarcopenia also develops without neurotrypsin and is not prevented by elevated levels of agrin. "
01/01/2013 - "Evidence is presented for a pathogenic role of the agrin/neurotrypsin system in a substantial subset of sarcopenia patients. "
01/01/2023 - "Accordingly, we explored whether genes encoding agrin (AGRN) and neurotrypsin (PRSS12) were associated with sarcopenia phenotypes: muscle mass, strength and plasma C-terminal agrin fragment (CAF). "

10/15/2021 - "In this study, we evaluated the role of motopsin in the neuropathological development of cognitive impairments following chemotherapy, also known as chemobrain. "

10/15/2021 - "Alternatively, motopsin may contribute to the neuropathology of chemobrain."
10/15/2021 - "In this study, we evaluated the role of motopsin in the neuropathological development of cognitive impairments following chemotherapy, also known as chemobrain. "

10/15/2021 - "Loss of motopsin function causes severe intellectual disability in humans. "
01/01/2018 - "Loss of motopsin gene function causes severe intellectual disability in humans and enhanced social behavior in mice. "
07/12/2013 - "A mental retardation gene, motopsin/prss12, modulates cell morphology by interaction with seizure-related gene 6."
12/01/2009 - "The loss of motopsin function causes nonsyndromic mental retardation in humans and impairs long-term memory formation in Drosophila. "
09/01/2008 - "A deletion in the neurotrypsin gene causes severe mental retardation in humans. "