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FL 1003
a methyl-furyl-butyrolactone compound
Also Known As:
FL1003
Networked:
2
relevant articles (
0
outcomes,
1
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Lactones: 1549
4-Butyrolactone: 81
FL 1003: 2
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Furans: 85
4-Butyrolactone: 81
FL 1003: 2
Related Diseases
1.
Acute Lung Injury
08/01/1997 - "
Treatment of animals with FL1003 significantly attenuated the inflammatory response associated with acute lung injury.
"
08/01/1997 - "
This study tested the hypothesis that treatment with FL1003, a butyrolactone with in vitro antioxidant properties, will down-regulate this response and abrogate acute lung injury.
"
08/01/1997 - "
Attenuation of acute lung injury caused by hind-limb ischemia-reperfusion injury by butyrolactone anti-inflammatory agent FL1003.
"
2.
Reperfusion Injury
08/01/1997 - "
Attenuation of acute lung injury caused by hind-limb ischemia-reperfusion injury by butyrolactone anti-inflammatory agent FL1003.
"
3.
Ischemia
08/01/1997 - "
Male Sprague-Dawley rats (n = 16) were divided into a surgical sham group (n = 4), a group that received 2 hours of ischemia by infrarenal aortic clip followed by 1 hour of reperfusion (n = 7), and an ischemia-reperfusion (I/R) group that received FL1003 100 mg/kg intravenously before ischemia (n = 5).
"
4.
Traumatic Brain Injuries (Traumatic Brain Injury)
01/01/1997 - "
The neuroprotective effect of an experimental anti inflammatory drug (FL1003, butyrolactone) was tested in a traumatic brain injury (TBI) model using BWC and MPO analysis.
"
Related Drugs and Biologics
1.
Antioxidants
2.
Neuroprotective Agents
3.
Anti-Inflammatory Agents (Anti-Inflammatories)
4.
salicylhydroxamic acid (SHAM)
Related Therapies and Procedures
1.
Surgical Instruments (Clip)