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GP 683

Also Known As:

4-(N-phenylamino)-5-phenyl-7-(5'-deoxyribofuranosyl)pyrrolo(2,3-d)pyrimidine; GP683

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrimidines: 510
    - GP 683: 2

Related Diseases

1.	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 09/01/1998 - "Delayed treatment with an adenosine kinase inhibitor, GP683, attenuates infarct size in rats with temporary middle cerebral artery occlusion."
2.	Ischemia 09/01/1998 - "Animals were injected intraperitoneally with vehicle, 0.5 mg/kg, 1.0 mg/kg, or 2.0 mg/kg of GP683 30, 150, and 270 minutes after the induction of ischemia by a researcher blinded to treatment group. " 09/01/1998 - "We studied a novel adenosine kinase inhibitor (AKI), GP683, in a rat focal ischemia model. "
3.	Infarction (Infarctions) 09/01/1998 - "Delayed treatment with an adenosine kinase inhibitor, GP683, attenuates infarct size in rats with temporary middle cerebral artery occlusion."
4.	Hypotension (Low Blood Pressure) 06/01/1999 - "GP683 showed little or no hypotension or bradycardia and minimal hypothermic effect at anticonvulsant doses. "
5.	Bradycardia 06/01/1999 - "GP683 showed little or no hypotension or bradycardia and minimal hypothermic effect at anticonvulsant doses. "

Related Drugs and Biologics

1.	Anticonvulsants (Antiepileptic Drugs)
2.	Adenosine Kinase

Related Therapies and Procedures

1.	Treatment Delay