vMIP-II

encoded by Kaposi's sarcoma-associated herpesvirus; chemokine that blocks calcium mobilization induced by endogenous chemokines; binds to both CC and CXC chemokine receptors; amino acid sequence in first source; GenBank U67775

Also Known As:

Networked: 30 relevant articles (0 outcomes, 4 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Gerstoft, J: 3 articles (08/2001 - 01/2000)
2.	Lüttichau, H R: 3 articles (08/2001 - 01/2000)
3.	Schwartz, T W: 3 articles (08/2001 - 01/2000)
4.	Detering, Lisa: 2 articles (01/2021 - 01/2016)
5.	Liu, Yongjian: 2 articles (01/2021 - 01/2016)
6.	Randolph, Gwendalyn J: 2 articles (01/2021 - 01/2016)
7.	Chen, Changjie: 2 articles (10/2018 - 04/2017)
8.	Chen, Sulian: 2 articles (10/2018 - 04/2017)
9.	Li, Yu: 2 articles (10/2018 - 04/2017)
10.	Wang, Haifeng: 2 articles (10/2018 - 04/2017)

Related Diseases

1.	Breast Neoplasms (Breast Cancer) 12/01/2020 - "The N-terminal polypeptide derived from vMIP-II exerts its antitumor activity in human breast cancer through CXCR4/miR-7-5p/Skp2 pathway." 11/01/2004 - "This study was to investigate effect of viral macrophage inflammatory protein-II (vMIP-II), an antagonist of CXCR4, on metastasis of breast cancer cell line MCF-7. " 10/31/2018 - "The N-terminal polypeptide derived from vMIP-II exerts its anti-tumor activity in human breast cancer by regulating lncRNA SPRY4-IT1."
2.	Neoplasm Metastasis (Metastasis) 11/01/2004 - "Adhesion and chemotaxis assays were also used to evaluate the effect of vMIP-II on MCF-7 cells in different steps of metastasis. " 11/01/2004 - "This study was to investigate effect of viral macrophage inflammatory protein-II (vMIP-II), an antagonist of CXCR4, on metastasis of breast cancer cell line MCF-7. "
3.	Leukemia 05/01/2003 - "We next treated a human monocytic leukemia cell line, THP-1, with purified recombinant vMIP-I and vMIP-II, or vMIP-I and vMIP-II fused with alkaline phosphatase to study Ca(2+) signalling and in vitro chemotaxis in response to these proteins. "
4.	Brain Injuries (Brain Injury) 12/01/2001 - "In the present study, the effects of vMIP-II and MIP-1alpha on ischemic brain injury were examined in mice to elucidate the roles of chemokines endogenously produced in the ischemic brain. "
5.	COVID-19 01/01/2021 - "Study on the promotion of lymphocytes in patients with COVID-19 by broad-spectrum chemokine receptor inhibitor vMIP-II and its Mechanism of signal transmission in vitro."

Related Drugs and Biologics

1.	Macrophage Inflammatory Proteins (Macrophage Inflammatory Protein 1)
2.	Chemokines
3.	Chemokine Receptors
4.	Proteins (Proteins, Gene)
5.	Chemokine CCL3
6.	Alkaline Phosphatase
7.	CC Chemokines
8.	Peptides (Polypeptides)
9.	Chemokine CCL5
10.	Chemokine CCL2 (Monocyte Chemoattractant Protein 1)

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)
2.	Analgesia