HOME
PRODUCTS
COMPANY
CONTACT
FAQ
Research
Dictionary
Pharma
Sign Up
FREE
or
Login
Username:
Password:
Remember login
Login
Send password reminder...
MDL 74721
structure in first source
Also Known As:
7-(dipropylamino)-5,6,7,8-tetrahydro-N-methyl-1-naphthalenemethanesulfonamide 2-butanedioate; MDL 74,721; MDL 74,721G; MDL-74,721; MDL-74,721G; MDL-74721
Networked:
2
relevant articles (
1
outcomes,
0
trials/studies)
Relationship Network
Bio-Agent Context: Research Results
Organic Chemicals: 133
Amides: 2428
Sulfonamides: 2809
MDL 74721: 2
Hydrocarbons: 1713
Cyclic Hydrocarbons: 97
Aromatic Hydrocarbons: 291
Polycyclic Aromatic Hydrocarbons: 2020
Naphthalenes: 18
Tetrahydronaphthalenes: 1
MDL 74721: 2
Sulfur Compounds: 278
Sulfones: 534
Sulfonamides: 2809
MDL 74721: 2
Polycyclic Compounds: 6
Polycyclic Aromatic Hydrocarbons: 2020
Naphthalenes: 18
Tetrahydronaphthalenes: 1
MDL 74721: 2
Related Diseases
1.
Migraine Disorders (Migraine)
10/08/1997 - "
In conclusion, MDL 74,721 demonstrates a preclinical profile consistent with anti-migraine efficacy.
"
10/08/1997 - "
MDL 74,721 (R)-2-(N1,N1-dipropylamino)-8-methylaminosulfonylmethyl-1,2,3,4-te trahydronaphthalene, a sulfonamidotetralin, has been found to exhibit a 10,000-fold greater potency in neurogenic versus vascular models of migraine.
"
10/08/1997 - "
The selectivity of MDL 74,721 in models of neurogenic versus vascular components of migraine.
"
04/01/1997 - "
MDL 74,721 (I), sumatriptan(II) and naratriptan(III) are new 5-HT1-like agonists that have potential as a novel treatment for migraine.
"
Related Drugs and Biologics
1.
Sumatriptan (Imigran)
2.
naratriptan