gp43 tumor-associated antigen
recognized by monoclonal antibody L92, associated with human melanoma; has immunoreactive tetrapeptide sequence Lys-Tyr-Gln-Ile
Also Known As:
tumor-associated antigen, gp43; 43-kDa protein, melanoma; gp43 antigen
Networked: 10
relevant articles (0 outcomes,
0 trials/studies)
Bio-Agent Context: Research Results
Experts
1. | Lopes, José Daniel:
3 articles
(03/2006 - 08/2003)
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2. | Mariano, Mario:
2 articles
(03/2006 - 10/2003)
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3. | Navarro, Italmar T:
1 article
(08/2013)
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4. | Omori, Aline M:
1 article
(08/2013)
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5. | Oliveira, Gabriela G:
1 article
(08/2013)
|
6. | Ono, Mario A:
1 article
(08/2013)
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7. | Ferreira, Jacqueline B:
1 article
(08/2013)
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8. | Camargo, Zoilo P:
1 article
(08/2013)
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9. | Belitardo, Donizeti R:
1 article
(08/2013)
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10. | Itano, Eiko N:
1 article
(08/2013)
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Related Diseases
1. | Paracoccidioidomycosis (South American Blastomycosis)
08/01/2003
- " Detection of circulating gp43 antigen in serum, cerebrospinal fluid, and bronchoalveolar lavage fluid of patients with paracoccidioidomycosis." 03/01/1995
- " Lack of reactivity of paracoccidioidomycosis sera in the double immunodiffusion test with the gp43 antigen: report of two cases." 08/01/2013
- " The humoral immune response to the gp43 antigen, the main antigen used for paracoccidioidomycosis serodiagnosis and seroepidemiology, was evaluated in two goats immunized with inactivated P. " 04/01/2007
- " By using a TEPITOPE algorithm, we selected and analyzed the T-cell responses of peripheral blood mononuclear cells from 29 paracoccidioidomycosis (PCM) patients to peptides of the immunodominant gp43 antigen of Paracoccidioides brasiliensis, the causative agent of PCM." 09/01/1991
- " Both forms are equally resistant to endogenous proteases at neutral pH. The gp43, itself, has a proteolytic activity at pH 5-6, but not at neutral pH. Deglycosylation with endoglycosidase H or tunicamycin preserved epitopes in the 38-kDa molecule reactive with (a) antibodies from patients with paracoccidioidomycosis, or rabbit immunized with the gp43 and (b) mouse monoclonal antibodies against the gp43 antigen. "
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2. | Melanoma (Melanoma, Malignant)
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3. | Infection
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4. | Hypersensitivity (Allergy)
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5. | Granuloma
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Related Drugs and Biologics