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NRA 0045
structure given in first source
Also Known As:
2-amino-4-(4-fluorophenyl)-5-(1-(4-(4-fluorophenyl)4-oxobutyl)pyrrolidin-3-yl)thiazole; NRA-0045; NRA0045
Networked:
2
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Azoles: 2138
Thiazoles: 392
NRA 0045: 2
Pyrrolidines: 115
NRA 0045: 2
Organic Chemicals: 133
Sulfur Compounds: 278
Thiazoles: 392
NRA 0045: 2
Experts
1.
Abekawa, T
: 1 article (09/2003)
2.
Honda, M
: 1 article (09/2003)
3.
Ito, K
: 1 article (09/2003)
4.
Koyama, T
: 1 article (09/2003)
Related Diseases
1.
Catalepsy
07/01/1997 - "
Catalepsy was dose-dependently and significantly induced by NRA0045 in rats, whereas NRA0045 did not exceed 50% induction even at the highest dose given (30 mg/kg i.p.).
"
2.
Ataxia (Dyssynergia)
09/01/2003 - "
NRA0045 (1 or 3 mg/kg) or clozapine (1 mg/kg) attenuated hyperlocomotion, stereotypy, and ataxia induced by PCP (7.5 mg/kg) without affecting behavior after saline injection.
"
Related Drugs and Biologics
1.
Clozapine (Clozaril)