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3-bromo-7-nitroindazole

Also Known As:

3-Br-7-NI

Networked: 9 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Pyrazoles: 61
      - Indazoles: 179
        3-bromo-7-nitroindazole: 9
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Indazoles: 179
      - 3-bromo-7-nitroindazole: 9

Experts

1.	Aricioglu, Feyza: 1 article (09/2012)
2.	Utkan, Tijen: 1 article (09/2012)
3.	Yazir, Yusufhan: 1 article (09/2012)
4.	Sharma, Shyam S: 1 article (01/2012)
5.	Srinivasan, Krishnamoorthy: 1 article (01/2012)
6.	Asaka, Y: 1 article (10/2001)
7.	Hara, A: 1 article (10/2001)
8.	Kusakari, J: 1 article (10/2001)
9.	Tabuchi, K: 1 article (10/2001)
10.	Tsuji, S: 1 article (10/2001)

Related Diseases

1.	Hyperthermia 09/11/2000 - "Pretreatment with the nNOS inhibitors S-methylthiocitrulline (SMTC; 10 mg/kg) or 3-bromo-7-nitroindazole (3-Br-7-NI; 20 mg/kg) before each METH injection did not affect the persistent hyperthermia produced by METH, but afforded protection against the depletion of dopaminergic markers. "
2.	Type 2 Diabetes Mellitus (MODY) 01/16/2012 - "The aim of the study was to investigate the neuroprotective potential of 3-bromo-7-nitroindazole (3-BNI), a potent and selective neuronal nitric oxide synthase (nNOS) inhibitor against ER stress and focal cerebral I/R injury associated with comorbid type 2 diabetes in-vivo. "
3.	Stroke (Strokes) 01/16/2012 - "3-Bromo-7-nitroindazole attenuates brain ischemic injury in diabetic stroke via inhibition of endoplasmic reticulum stress pathway involving CHOP."
4.	Status Epilepticus (Complex Partial Status Epilepticus) 01/01/1997 - "3-Br-7-NI and TRIM decreased the frequency of status epilepticus and mortality, while TRIM. " 01/01/1997 - "The latencies to onsets of seizures, status epilepticus, and mortality were significantly prolonged by all three NOS inhibitors, while duration of seizures was reduced by 3-Br-7-NI and TRIM. "
5.	Septic Shock (Toxic Shock Syndrome) 09/01/1999 - "The (DETC)(2)-Fe(II)-NO signal in all the tissues of septic-shock rats was markedly suppressed by preadministration of the nitric oxide synthase (NOS) inhibitors, N(G)-monomethyl-L-arginine (L-NMMA) or 3-bromo-7-nitroindazole, suggesting that the NO detected from brain tissue was produced enzymatically by NOS. "

Related Drugs and Biologics

1.	S-methylthiocitrulline
2.	Nitric Oxide Synthase Type I (Neuronal Nitric Oxide Synthase)
3.	Arginine (L-Arginine)
4.	imidazole
5.	omega-N-Methylarginine (NG Monomethyl L Arginine)
6.	Nitric Oxide Synthase (NO Synthase)
7.	Cyclooxygenase Inhibitors
8.	Sucrose (Saccharose)
9.	Nitrites
10.	Iron