mapacalcine

a dimeric protein from Cliona vastifica sponge, which specifically blocks a non-L-type calcium channel; NW 19kDa; partial amino acid sequence given in first source

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Hugues, Michel: 2 articles (01/2013 - 05/2003)
2.	Borsotto, Marc: 1 article (01/2013)
3.	Gallois, Bernard: 1 article (01/2013)
4.	Gallois, Djamila Sedjelmaci Bernard: 1 article (01/2013)
5.	Heurteaux, Catherine: 1 article (01/2013)
6.	Moha Ou Maati, Hamid: 1 article (01/2013)
7.	Sedjelmaci, Djamila: 1 article (01/2013)
8.	Widmann, Catherine: 1 article (01/2013)
9.	Crenesse, Dominique: 1 article (05/2003)
10.	Ferre, Catherine: 1 article (05/2003)

Related Diseases

1.	Hypoxia (Hypoxemia) 01/01/2013 - "Here, we showed that mapacalcine, a homodimeric peptide purified from the marine sponge Cliona vastifica, is able to protect mouse cortical neurons against hypoxia. " 01/01/2013 - "Mapacalcine protects mouse neurons against hypoxia by blocking cell calcium overload." 05/01/2003 - "Mapacalcine specifically blocks hypoxia-induced calcium influx in rat hepatocytes."
2.	Stroke (Strokes) 01/01/2013 - "Our data indicate that mapacalcine is a promising molecule for stroke treatment. "
3.	Dental Calculus 04/01/1998 - "Mapacalcine was ineffective on T-type and L-type Ca2+ currents present on rat portal vein myocytes [Morel, Drobecq, Sautière, Tartar, Mironneau, Qar, Lavie, and Hugues (1997) Mol. "

Related Drugs and Biologics

1.	Calcium
2.	Peptides (Polypeptides)