YM 268

structure given in first source

Also Known As:

YM-268; YM268; bis(4-((2,4-dioxo-5-thiazolidinyl)methyl)-phenyl)methane

Networked: 1 relevant articles (1 outcomes, 0 trials/studies)

1.	Insulin Resistance 12/01/1997 - "These data suggested that one of the mechanisms by which YM268 improved insulin resistance in obese Zucker rats was to normalize the decreased GLUT4 content in the adipose tissue." 12/01/1997 - "Insulin sensitizer YM268 ameliorates insulin resistance by normalizing the decreased content of GLUT4 in adipose tissue of obese Zucker rats."
2.	Glucose Intolerance 12/01/1997 - "The administration of YM268 at a dose of 10 mg/kg for 2 weeks ameliorated hyperglycaemia, hyperinsulinaemia, and impaired glucose tolerance after glucose load in obese rats. "