mutein 6

01/01/1999 - "Ultrastructure of lung granulocytes in the development of the primary focus of Morris hepatoma 5123 subjected to the action of rhTNF-alpha and its mutein VI."
01/01/1997 - "Ultrastructural analysis of pulmonary capillaries after mutein VI rhTNF-alpha administration into Morris hepatoma."
01/01/1997 - "BAL-isolated cells after administration of mutein VI rhTNF-alpha into Morris hepatoma."
01/01/1996 - "Also, the ultrastructural changes observed in the pulmonary tissue indicate the possibility of peripheral action of mutein VI after its administration to rats carrying the Morris hepatoma."
01/01/1996 - "Ultrastructural evaluation of Morris hepatoma metastases to the lungs after local administration of Mutein VI hrecTNF-alpha."

01/01/1998 - "Our study indicates that TNF-alpha and its mutein VI decrease the antileukemic effect of gemcitabine on murine leukemias L1210 and P388."
01/01/1998 - "Interactions of 2',2'-diflurodeoxycytidine (gemcitabine) with tumor necrosis factor alpha or its mutein VI in murine leukemias L1210 and P388."

01/01/1996 - "The animals given mutein VI compared to those injected with PBS demonstrated a decrease in the number of metastases. "
01/01/1996 - "Ultrastructural evaluation of Morris hepatoma metastases to the lungs after local administration of Mutein VI hrecTNF-alpha."
01/01/1996 - "The mutein VI-hrec TNF-alpha was found to block the neoplastic process, illustrated by a reduction in the volume of lung parenchyma occupied by neoplastic metastases. "

02/01/2000 - "three times a week with 10 micrograms/mice of rhTNF-alpha, mutein V or mutein VI for two weeks, starting on the 4th day after tumor inoculation. "

01/01/1995 - "We investigated the influence of 2-chlorodeoxyadenosine (2-CdA) in combination with tumour necrosis factor-alpha (TNFalpha) or its mutein VI, which differs from the native molecule by N-terminal amino acid composition, on the survival time of mice inoculated with leukaemia L1210 or P388. "