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S 28828

an analog of imiquimod; structure given in first source

Also Known As:

1-butyl-2-ethoxymethyl-1H-imidazo(A,5-c)quinolin-4-amine hydrochloride; S-28828

Networked: 3 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Quinolines: 146
      - Aminoquinolines: 29
        S 28828: 3

Experts

1.	Goyal, Sagar M: 1 article (07/2002)
2.	Miller, Richard L: 1 article (07/2002)
3.	Patnayak, Devi P: 1 article (07/2002)
4.	Rautenschlein, Silke: 1 article (07/2002)
5.	Sharma, Jagdev M: 1 article (07/2002)
6.	Sheikh, Anwar M: 1 article (07/2002)
7.	Miller, R L: 1 article (06/2000)
8.	Rautenschlein, S: 1 article (06/2000)
9.	Sharma, J M: 1 article (06/2000)

Related Diseases

1.	Body Weight (Weight, Body) 11/24/1998 - "We examined the effect of a high dose (100 mg kg(-1) body weight) of S-28828 on the pathogenesis of E. " 07/01/2002 - "The combined inoculation of S-28828 (5 mg/kg body weight) and P41 resulted in a significant reduction in the incidence of virus-induced clinical signs in comparison with birds that received P41 without immunomodulator (P < 0.05). "
2.	Shock 11/24/1998 - "coli by S-28828 may have been due to the massive release of cytokines inducing a shock-like syndrome in infected turkeys."
3.	Hyperplasia 06/01/2000 - "By itself, S-28828 induced a strong reaction in the spleen characterized by hyperplasia of the red and white pulps as well as an increase in lymphoid cell aggregations. "
4.	Enteritis 06/01/2000 - "Oral administration of S-28828 before the time of virus inoculation suppressed significantly (P<0.05) the replication of hemorrhagic enteritis virus (HEV) in turkeys. "

Related Drugs and Biologics

1.	Immunologic Factors (Immunomodulators)
2.	Cytokines

Related Therapies and Procedures

1.	Oral Administration