8-phenyl-2-(di-n-propylamino)tetralin

02/01/1997 - "In the present study, we examined whether abrogation of NK-TR expression by retroviral infection of primary human or mouse NK cells with virus-producing antisense NK-TR also would demonstrate loss of non-MHC-restricted killing and whether the NK-TR was associated with KIR function in humans or with Ly-49 in the mouse. "
05/15/2002 - "Therefore, we have correlated the frequencies of cells expressing the pan-NK marker DX5 and subsets bearing inhibitory Ly-49 receptors with worm survival and cytokine production during infection with Litomosoides sigmodontis in BALB/c mice (H2(d)), the only fully permissive model of filariasis. "

10/15/2003 - "Murine NK cells express the Ly-49 family of class I MHC-binding receptors that control their ability to lyse tumor or virally infected host target cells. "
12/01/1996 - "While Ly-49C+ NK cells have been demonstrated to mediate the specific rejection of H-2d bone marrow allografts, the role of the Ly-49 G2+ NK subset is unclear because depletion of this subset in vivo did not affect splenic NK activity against tumor targets. "
02/01/1998 - "Abs to Ly-49A and G2 or their respective class I ligands blocked the negative signals mediated via the Ly-49 receptors and increased IFN-gamma and granulocyte-macrophage CSF production after interaction of these T cells with H-2Dd-expressing tumor targets. "
02/28/1995 - "The Ly-49 molecule has been shown to interact with major histocompatibility complex (MHC) class I molecules, and the lytic function of Ly-49+ natural killer (NK) cells from C57BL/6 (H-2b) mice is inhibited by the recognition of H-2Dd on tumor target cells. "
10/01/1990 - "The Ly-49 (A1, YE1/48) Ag is a disulfide-linked dimer with 44-kDa subunits, and is expressed on the cell surface of rare T cell tumors of C57BL/6 origin. "

06/01/1994 - "Induction of Ly-49 on an interspecies hybridoma between differentiation stage specific murine T cells and a rat T lymphoma."
03/01/1994 - "The Ly-49 expressing EL4 lymphoma bound Dd, Dk, and Kb, but not Kd, Kk, or Db, thus demonstrating a restricted pattern of class I adhesion. "
03/01/1994 - "Adhesion to class I molecules was not found with T lymphomas lacking Ly-49 expression. "
03/01/1994 - "Ly-49 is a recently identified cell surface molecule expressed on a subpopulation of natural killer (NK) cells and certain T lymphomas. "
03/01/1994 - "Ly-49 mediates EL4 lymphoma adhesion to isolated class I major histocompatibility complex molecules."

06/01/2006 - "Activating, DAP12-coupled members of the Ly-49 family of NK cell receptors help control viral infections in mice. "

06/01/1994 - "Ly-49 can be expressed in interspecies hybridoma cells resulting from the fusion of Ly-49 negative lymphoid cells from normal mice and Ly-49 negative T cells from the rat thymoma W/Fu(C58NT)D (C58). "