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6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase-7,8-dihydropteroate synthase

bifunctional enzyme involved in folate biosynthesis in plants; amino acid sequence in first source; GenBank Y08611 (Pisum sativum)

Also Known As:

HPPK-DHPS; PPPK-DHPS; hydroxymethyldihydropterin-pyrophosphokinase-dihydropteroate synthase

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Macromolecular Substances: 97
- Multiprotein Complexes: 125
  - Multienzyme Complexes: 8
    - 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase-7,8-dihydropteroate synthase: 2
Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Multienzyme Complexes: 8
    - 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase-7,8-dihydropteroate synthase: 2

Related Diseases

1.

10/04/2023 - "These results corroborate that the hppk-dhps gene is a novel amplification target for the detection of human malaria. "
10/04/2023 - "A Novel Nested Multiplex Polymerase Chain Reaction Assay for Malaria Diagnosis Using the Hydroxymethyl Dihydropterin Pyrophosphokinase-Dihydropteroate Synthase (hppk-dhps) Gene."
09/01/1994 - "Sequence variation of the hydroxymethyldihydropterin pyrophosphokinase: dihydropteroate synthase gene in lines of the human malaria parasite, Plasmodium falciparum, with differing resistance to sulfadoxine."

Related Drugs and Biologics

1.	Sulfadoxine (Sulformethoxine)
2.	Dihydropteroate Synthase (Dihydropteroate Synthetase)