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phebestin

produced by Streptomyces sp. MJ716-m3; structure given in first source

Also Known As:

(2S,3R)-3-amino-2-hydroxy-4-phenylbutanoyl-valyl-phenylalanine

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Oligopeptides: 519
    - phebestin: 2

Experts

1.	Ansorge, Siegfried: 1 article (10/2007)
2.	Bank, Ute: 1 article (10/2007)
3.	Bukowska, Alicja: 1 article (10/2007)
4.	Helmuth, Martin: 1 article (10/2007)
5.	Ittenson, Annelore: 1 article (10/2007)
6.	Lendeckel, Uwe: 1 article (10/2007)
7.	Malfertheiner, Peter: 1 article (10/2007)
8.	Naumann, Michael: 1 article (10/2007)
9.	Reinhold, Dirk: 1 article (10/2007)
10.	Shakespeare, Ann: 1 article (10/2007)

Related Diseases

1.	Parasitemia 01/01/2023 - "yoelii 17XNL-infected mice with administrations of 20 mg/kg phebestin, once daily for 7 days, resulted in significantly lower parasitemia peaks in the phebestin-treated group (19.53%) than in the untreated group (29.55%). "
2.	Malaria 01/01/2023 - "These results indicate that phebestin is a promising candidate for development as a potential therapeutic agent against malaria."
3.	Colitis 10/01/2007 - "Furthermore, transfer of CD4+CD25+ T-cells exposed to phebestin for a short time ex vivo significantly reduced the mouse colitis disease activity index. " 10/01/2007 - "We investigated whether phebestin also produced this effect in CD4+CD25+ T-cells and whether phebestin-treated CD4+CD25+ T-cells were capable of ameliorating acute colitis in mice. " 10/01/2007 - "The in vivo role of phebestin-exposed CD4+CD25+ T-cells was studied in sodium dextran sulfate-induced acute colitis in mice. "

Related Drugs and Biologics

1.	Dextran Sulfate