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methyl pyruvate

Networked: 10 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Carboxylic Acids: 973
  - Keto Acids: 203
    - Pyruvates: 20
      - methyl pyruvate: 10

Experts

1.	Alzahrani, Abdulhakeem: 1 article (07/2021)
2.	Chen, Heather: 1 article (07/2021)
3.	Green, Andrew: 1 article (07/2021)
4.	Martz, Kailey: 1 article (07/2021)
5.	Warriner, Keith: 1 article (07/2021)
6.	Wu, Xueyang: 1 article (07/2021)
7.	Bekhit, Michael: 1 article (01/2020)
8.	Gorski, Waldemar: 1 article (01/2020)
9.	Chen, Hongyan: 1 article (01/2017)
10.	Li, Siqi: 1 article (01/2017)

Related Diseases

1.	Starvation 02/01/2009 - "In keeping with this bioenergetic explanation for ceramide toxicity, methyl pyruvate, a membrane-permeable nutrient, protects cells from ceramide-induced starvation. " 11/01/1995 - "These results suggest that methyl pyruvate could be used as an insulinotropic agent to bypass site-specific defects of D-glucose metabolism in the B-cell, such as those found in starvation or non-insulin-dependent diabetes mellitus."
2.	Neoplasms (Cancer) 03/13/2014 - "By contrast, addition of methyl pyruvate to supplement TCA substrates protected Tet-treated tumor cells. " 01/01/2017 - "We conclude that methyl pyruvate may preferentially kill cancer cells and protect normal cells during chemotherapy."
3.	Infections 01/01/2020 - "Electroanalysis of Infection with Methyl Pyruvate." 01/01/2017 - "Methyl pyruvate (MP) inhibited conversion of LC3I to LC3II and accumulation of GFP-LC3, which could reverse the energy loss caused by DEV infection. " 01/01/2020 - "The discovery of infection enzyme leukocyte esterase (LE) hydrolyzing a mitochondrial substrate methyl pyruvate (MP) was explored in the development of electroanalytical methods for LE in human biofluids. "
4.	Type 2 Diabetes Mellitus (MODY) 11/01/1995 - "These results suggest that methyl pyruvate could be used as an insulinotropic agent to bypass site-specific defects of D-glucose metabolism in the B-cell, such as those found in starvation or non-insulin-dependent diabetes mellitus." 11/01/2001 - "Potentiation and prolongation of the insulinotropic action of glucagon-like peptide 1 by methyl pyruvate or dimethyl ester of L-glutamic acid in a type 2 diabetes animal model."
5.	Shock 07/01/2021 - "The progress of type II persisters of Escherichia coli O157:H7 to a non-culturable state during prolonged exposure to antibiotic stress with revival being aided through acid-shock treatment and provision of methyl pyruvate."

Related Drugs and Biologics

1.	Glucose (Dextrose)
2.	Glucagon-Like Peptide 1 (GLP 1)
3.	Genistein
4.	Glutamic Acid (Glutamate)
5.	Fatty Acids (Saturated Fatty Acids)
6.	Esters
7.	Enzymes
8.	Ceramides
9.	Anti-Bacterial Agents (Antibiotics)
10.	Acids

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)