Pro-Opiomelanocortin

A 30-kDa protein synthesized primarily in the ANTERIOR PITUITARY GLAND and the HYPOTHALAMUS. It is also found in the skin and other peripheral tissues. Depending on species and tissues, POMC is cleaved by PROHORMONE CONVERTASES yielding various active peptides including ACTH; BETA-LIPOTROPIN; ENDORPHINS; MELANOCYTE-STIMULATING HORMONES; and others (GAMMA-LPH; CORTICOTROPIN-LIKE INTERMEDIATE LOBE PEPTIDE; N-terminal peptide of POMC or NPP).

Also Known As:

Proopiomelanocortin; POMC; ACTH-Endorphin Precursor; ACTH-beta-Lipotropin Precursor; Corticotropin-beta-Lipotropin Precursor; Endorphin-ACTH Precursor; Opiocortin; Pre-POMC; Pre-pro-opiocortin; Preproopiomelanocortin; Pro-ACTH-Endorphin; Pro-Opio-Melanocortin; Proopiocortin; ACTH Endorphin Precursor; ACTH beta Lipotropin Precursor; Corticotropin beta Lipotropin Precursor; Endorphin ACTH Precursor; Pre POMC; Pre pro opiocortin; Pro ACTH Endorphin; Pro Opio Melanocortin; Pro Opiocortin; Pro Opiomelanocortin; Pro-Opiocortin; Opiomelanocortin, pro-

Hormones, Hormone Substitutes, and Hormone Antagonists
- Hormones: 80400
  - Peptide Hormones: 1347
    - Pituitary Hormones: 601
      - Anterior Pituitary Hormones: 187
        Pro-Opiomelanocortin: 1936
    - Hypothalamic Hormones: 68
      - Pro-Opiomelanocortin: 1936
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Protein Precursors: 37
    - Pro-Opiomelanocortin: 1936
  - Nerve Tissue Proteins: 2
    - Neuropeptides: 6772
      - Hypothalamic Hormones: 68
        Pro-Opiomelanocortin: 1936
- Peptides: 82426
  - Neuropeptides: 6772
    - Hypothalamic Hormones: 68
      - Pro-Opiomelanocortin: 1936
  - Peptide Hormones: 1347
    - Pituitary Hormones: 601
      - Anterior Pituitary Hormones: 187
        Pro-Opiomelanocortin: 1936
    - Hypothalamic Hormones: 68
      - Pro-Opiomelanocortin: 1936

Lys-gamma(2) MSH

Bio-Agent Context: Research Results