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hypertonic saline-dextran solution

contains 4ml/kg, 2,400 mOsm/L NaCl in 6% dextran-70; used to resuscitate dehydrated calves with diarrhea

Also Known As:

HSD solution

Networked: 15 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Basu, Samar: 1 article (11/2006)
2.	Miclescu, Adriana: 1 article (11/2006)
3.	Wiklund, Lars: 1 article (11/2006)
4.	Alpar, Emin Kaya: 1 article (05/2004)
5.	Killampalli, Vijay Vardhan: 1 article (05/2004)
6.	Boros, Mihály: 1 article (04/2004)
7.	Csonka, Endre: 1 article (04/2004)
8.	Eszlári, Edgár: 1 article (04/2004)
9.	Kaszaki, József: 1 article (04/2004)
10.	Kucsa, Katalin: 1 article (04/2004)

Related Diseases

1.	Hypovolemia 01/01/1996 - "Use of hypertonic saline-dextran solution to resuscitate hypovolemic calves with diarrhea." 01/01/1990 - "The introduction of a 7.5% hypertonic saline/6% dextran 70 (HSD) solution into clinical trials for the treatment of hypovolemic states, and the past concerns regarding the possible interference of dextran with blood serology, prompted us to investigate the effects of HSD on human red-cell typing and stability. " 02/01/1992 - "We compared a hypertonic saline-dextran solution (7.5% NaCl/6% dextran-70) with 0.9% NaCl (normal saline) for treatment of intraoperative hypovolemia. " 02/01/1992 - "Hypertonic saline-dextran solution resuscitation of intraoperative hypovolemia is performed effectively with smaller fluid and sodium loads, and is devoid of the deleterious effects associated with fluid accumulation induced by a conventional isotonic solution regimen."
2.	Sepsis (Septicemia) 11/01/2002 - "Hypertonic saline/dextran solution may improve cardiovascular performance in severe sepsis without significant side effects. " 11/01/2002 - "Acute haemodynamic effects of a hypertonic saline/dextran solution in stable patients with severe sepsis." 01/01/1991 - "In the pre-clinical setting, small-volume resuscitation by means of hypertonic saline/dextran solution is aimed at the rapid normalization of the compromised microcirculation and, thus, at the prevention of late complications such as sepsis and multiple system organ failure. " 11/01/2002 - "To study the haemodynamic effects of a hypertonic saline/dextran solution compared with a normal saline solution in patients with severe sepsis. "
3.	Shock 05/01/2004 - "Recent interest in the usage of HSD solution has confirmed that they have a place in resuscitation of a patient in shock. " 01/15/1997 - "Evaluation of a hypertonic saline-dextran solution for treatment of dogs with shock induced by gastric dilatation-volvulus." 06/01/1991 - "In an effort to find the best hypertonic saline-dextran solution (HSD) for prehospital use, 33 chronically catheterized sheep were bled using a fixed pressure shock model (50 mm Hg x 2 hours) and resuscitated with 4 ml/kg of HSD solution (2-minute bolus). " 01/15/1997 - "To test the hypothesis that small volumes of hypertonic saline-dextran (HSD) solution can be used to effectively resuscitate dogs in shock induced by gastric dilatation-volvulus (GDV), and, compared with administration of large volumes of lactated Ringer's solution (LRS), can be used to limit the overall volume of fluid needed for resuscitation. "
4.	Hemorrhagic Shock 01/01/1991 - "Treatment of hemorrhagic shock with intraosseous or intravenous infusion of hypertonic saline dextran solution." 04/01/2004 - "Hemorrhagic shock (for 60 min) was followed by resuscitation with saline, hypertonic saline-Dextran solution (HSD, 7.2% NaCl-10% Dextran, 4 mL/kg), or HSD supplemented with the selective endothelin-A receptor antagonist ETR-p1/fl peptide (100 nmol/kg), respectively. "
5.	Diarrhea 01/01/1996 - "Use of hypertonic saline-dextran solution to resuscitate hypovolemic calves with diarrhea." 07/01/1998 - "Comparison of hypertonic saline-dextran solution and lactated Ringer's solution for resuscitating severely dehydrated calves with diarrhea."

Related Drugs and Biologics

1.	Dextrans (Dextran)
2.	Solutions
3.	Saline Solution
4.	Ringer's Solution
5.	Ringer's Lactate
6.	hypertonic saline-dextran solution
7.	Therapeutic Uses
8.	Endothelin A Receptor
9.	Sodium
10.	Peptides (Polypeptides)

Related Therapies and Procedures

1.	Resuscitation
2.	Cardiopulmonary Resuscitation (CPR)
3.	Intravenous Infusions
4.	Fluid Therapy (Oral Rehydration Therapy)