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tris(4-chlorophenyl)methanol

Also Known As:

TCPM compound

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Trityl Compounds
        tris(4-chlorophenyl)methanol: 1

Related Diseases

1.

Body Weight (Weight, Body)

01/01/1997 - "The systemic toxicity of tris(4-chlorophenyl)methanol (TCPM) was studied in male and female rats following 4 weeks dietary exposure dosed at 1, 10 and 100 ppm. An increased spleen to body weight ratio was observed in males at 10 and 100 ppm and in females at 100 ppm. An increased liver to body weight ratio was detected in both sexes at 100 ppm. Dose-related increases in hepatic Phase-I (AH, APDM, EROD and PROD) and Phase-II (UDPGT, GST) enzyme activities were observed generally at 10 and 100 ppm, with the elevation in PROD activity being the most marked. "

Related Drugs and Biologics

1.	Cytochrome P-450 CYP1A1 (CYP1A1)
2.	Cytochrome P-450 CYP2B1 (PROD)
3.	Enzymes
4.	Dihydrotachysterol (AT 10)