HIV Envelope Protein gp120

External envelope protein of the human immunodeficiency virus which is encoded by the HIV env gene. It has a molecular weight of 120 kDa and contains numerous glycosylation sites. Gp120 binds to cells expressing CD4 cell-surface antigens, most notably T4-lymphocytes and monocytes/macrophages. Gp120 has been shown to interfere with the normal function of CD4 and is at least partly responsible for the cytopathic effect of HIV.

Also Known As:

HIV Envelope Glycoprotein gp120; gp120 Envelope Glycoprotein, HIV; HTLV III gp120; gp120, HTLV-III; Envelope Glycoprotein gp120, HIV; HTLV-III gp120; env Protein gp120, HIV; gp120(HIV)

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Viral Proteins: 4250
    - Viral Antigens: 3254
      - HIV Antigens: 144
        HIV Envelope Protein gp120: 42
    - Viral Structural Proteins: 171
      - Viral Envelope Proteins: 291
        env Gene Products: 219
        Human Immunodeficiency Virus env Gene Products
        HIV Envelope Protein gp120: 42
    - Retroviridae Proteins: 7
      - env Gene Products: 219
        Human Immunodeficiency Virus env Gene Products
        HIV Envelope Protein gp120: 42
      - Human Immunodeficiency Virus Proteins: 143
        Human Immunodeficiency Virus env Gene Products
        HIV Envelope Protein gp120: 42
Biological Factors: 2472
- Antigens: 143924
  - Viral Antigens: 3254
    - HIV Antigens: 144
      - HIV Envelope Protein gp120: 42

KAB 121

Bio-Agent Context: Research Results