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2-thienyl 2'-hydroxyphenyl ketone

structure given in first source

Also Known As:

C85

Networked: 11 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Ketones: 2618
  - 2-thienyl 2'-hydroxyphenyl ketone: 11
- Sulfur Compounds: 278
  - Thiophenes: 257
    - 2-thienyl 2'-hydroxyphenyl ketone: 11
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Thiophenes: 257
    - 2-thienyl 2'-hydroxyphenyl ketone: 11

Experts

1.	Dabrowska, Magdalena: 5 articles (01/2019 - 01/2007)
2.	Rode, Wojciech: 5 articles (01/2019 - 01/2007)
3.	Skoneczny, Marek: 2 articles (01/2019 - 10/2011)
4.	Uram, Lukasz: 2 articles (01/2019 - 01/2018)
5.	Sikora, Ewa: 2 articles (01/2018 - 10/2009)
6.	Skierski, Janusz: 2 articles (10/2009 - 01/2007)
7.	Arnold, Ingo: 1 article (03/2020)
8.	Dierkes, Christian: 1 article (03/2020)
9.	Gehrke, Thorsten: 1 article (03/2020)
10.	Haas, Holger: 1 article (03/2020)

Related Diseases

1.	Neoplasms (Cancer) 05/01/2013 - "This study provides up-to-date and detailed cancer survival estimates of German patients with non-Hodgkin lymphoma (NHL, International Statistical Classification of Diseases 10th Revision [ICD-10] codes C82-C85) based on data from 11 cancer registries. " 01/01/2019 - "Lack of extensive chromosomal instability in C85 cells is hypothesized to be attributed to the presence of the wild-type tumor suppressor p53 protein. " 03/01/2020 - "Three cases of periprosthetic malignant neoplasia (SLIM-type VIII) were detected: one case of small B lymphocytic lymphoma/BCLL (C85.9; ICD-O: 9670/3), one case of diffuse large B‑cell lymphoma/DLBCL (C83.3; ICD‑O 9680/3), and one case of anaplastic large cell lymphoma (C84.7; ICD-O: 9714/3), with the latter ones being the causes for joint replacement , which indicates that malignant neoplasia is a very rare cause of endoprosthetic joint replacement (n = 2; 0.05%). "
2.	Colonic Neoplasms (Colon Cancer) 10/01/2011 - "Cellular functions accompanying establishment of premature senescence in methotrexate-treated human colon cancer C85 cells are deciphered in the present study from validated competitive expression microarray data, analyzed with the use of Ingenuity Pathways Analysis (IPA) software. " 01/01/2019 - "Human colon cancer C85 cell response to methotrexate has been documented previously to take on a form of reversible premature senescence. " 01/01/2018 - "The response of human colon cancer C85 cells to methotrexate takes the form of reversible growth arrest of the type of stress-induced senescence. "
3.	Non-Hodgkin Lymphoma (Lymphosarcoma) 05/01/2013 - "This study provides up-to-date and detailed cancer survival estimates of German patients with non-Hodgkin lymphoma (NHL, International Statistical Classification of Diseases 10th Revision [ICD-10] codes C82-C85) based on data from 11 cancer registries. "
4.	Adenocarcinoma 01/26/2007 - "Treatment with 1 microM methotrexate for 48 h of human colorectal adenocarcinoma C85 cells, stably transfected to express EGFP, caused 5-fold increase in EGFP fluorescence assayed by flow cytometry with no distinct increase in EGFP protein level. " 10/18/2009 - "Human colorectal adenocarcinoma C85 cells, treated with high dose methotrexate (1 microM; IC(50)=51 nM), undergo accelerated senescence, as the cells (i) are growth arrested at the G(1) and S phases of the cell cycle, (ii) are SA-beta-galactosidase-positive, (iii) show induced expression of p21(waf1/cip1) and decreased expression of p16(INK4a), and (iv) show DNA synthesis continued at the reduced level. "
5.	Overweight 10/01/2007 - "BMI values indicating overweight in the Lodz children (c85) were more similar to the international norms of IOTF (maximal difference around 5%). "

Related Drugs and Biologics

1.	Methotrexate (Mexate)
2.	Cyclin-Dependent Kinase Inhibitor p16
3.	Proteins (Proteins, Gene)
4.	Hepatitis B e Antigens
5.	DNA (Deoxyribonucleic Acid)
6.	beta-Galactosidase (Lactaid)
7.	enhanced green fluorescent protein

Related Therapies and Procedures

1.	Replacement Arthroplasty