BRCA1-delta11b

MW 110 kDa; a splice variant of BRCA1 missing the majority of exon 11 including the nuclear localization signal (NLS); amino acid sequence given in first source; GenBank U64805

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Related Diseases

1.	Carcinogenesis 01/09/1997 - "Taken together our results suggest that full-length BRCA1 and BRCA1-delta11b may have distinct roles in cell growth regulation and tumorigenesis."
2.	Neoplasms (Cancer) 01/09/1997 - "Interestingly, BRCA1-delta11b message was greatly reduced or absent in several breast and ovarian tumor lines relative to exon 11 transcripts and a delta9,10 splice variant. "