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T 0632
structure given in first source
Also Known As:
3-(1-(2-fluorophenyl)-2,3-dihydro-3-((3-isoquinolinyl)carbonyl)amino-6-methoxy-2-oxo-1H-indole)propanoate; T-0632
Networked:
2
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
Fused-Ring Heterocyclic Compounds
2-Ring Heterocyclic Compounds
Indoles: 200
T 0632: 2
Related Diseases
1.
Pancreatitis
02/01/1997 - "
These results suggest that CCK plays an important role in progression and aggravation of acute pancreatitis, and T-0632 may have a therapeutic value in these disease states.
"
02/01/1997 - "
We conclude that T-0632 showed preventive effects on all of these pancreatitis models by oral or intraduodenal administration.
"
02/01/1997 - "
Effect of T-0632, a cholecystokininA receptor antagonist, on experimental acute pancreatitis.
"
09/26/1996 - "
The effect of T-0632 for caerulein-induced pancreatitis was 4-fold more potent than that for gallbladder emptying.
"
09/26/1996 - "
In mice, orally administered T-0632 prevented caerulein-induced pancreatitis, CCK-8-induced inhibition of gastric emptying and CCK-8-induced gallbladder emptying in dose-dependent manners with ED50 values of 0.028, 0.04, and 0.12 mg/kg, respectively.
"
Related Drugs and Biologics
1.
Ceruletide
2.
Cholecystokinin A Receptor
3.
Sodium
4.
Protease Inhibitors (Protease Inhibitor)
5.
Propionates
6.
Cholecystokinin (Pancreozymin)
7.
Amylases
8.
loxiglumide
9.
camostat
10.
indole
Related Therapies and Procedures
1.
Ligation