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GL 2021

a methyl derivative of GL-522-Y-1

Also Known As:

GL-2021

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Boczkowska-Radziwon, B: 1 article (07/2000)
2.	Breddin, H K: 1 article (07/2000)
3.	Giedrojc, J: 1 article (07/2000)
4.	Kloczko, J: 1 article (07/2000)
5.	Radziwon, P: 1 article (07/2000)
6.	Schenk, J: 1 article (07/2000)
7.	Wojtukiewicz, M Z: 1 article (07/2000)

Related Diseases

1.	Lymphoid Leukemia 01/01/1998 - "GL-2021, GL-2029, GL-2041 and GL-2063, were selected for a mode of action study in L1210 lymphoid leukemia cells at concentration of 25muM to 100muM for 60 min. The agents did not alkylate bases of ct-DNA, cause intercalation between base pairs, produce cross linking of ct-DNA strands or generate free radicals although L1210 DNA fragmentation was observed after 24 hr incubation. "
2.	Thrombosis (Thrombus) 07/01/2000 - "The effects of polysulfonate derivative (GL 2021) on coagulation in vitro and thrombosis in vivo."

Related Drugs and Biologics

1.	Free Radicals
2.	DNA (Deoxyribonucleic Acid)