somatostatin receptor 3

Asp(124) in SSTR3 is essential for SST-14 binding; has been sequenced; partial amino acid sequence given in first source

Also Known As:

SSTR3 receptor; receptor 3, somatostatin; somatostatin receptor-3; somatostatin receptors 3

Networked: 8 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Barbeito, Pablo: 1 article (01/2021)
2.	Garcia-Gonzalo, Francesc R: 1 article (01/2021)
3.	Kobayashi, Tetsuo: 1 article (01/2021)
4.	Martin-Morales, Raquel: 1 article (01/2021)
5.	Moreno, Paula: 1 article (01/2021)
6.	Mykytyn, Kirk: 1 article (01/2021)
7.	Tachibana, Yuki: 1 article (01/2021)
8.	Günther, Thomas: 1 article (06/2016)
9.	Kliewer, Andrea: 1 article (06/2016)
10.	Lehmann, Andreas: 1 article (06/2016)

Related Diseases

1.	Neoplasms (Cancer) 01/01/2010 - "In stomach tumors, an expression of somatostatin receptor 3 (SSTR3) is diminished or completely lost. " 01/01/2021 - "Serotonin receptor 6 (HTR6) and somatostatin receptor 3 (SSTR3) are two brain-enriched ciliary GPCRs involved in cognition and pathologies such as Alzheimer's disease and cancer. " 06/01/1993 - "We have formed the following conclusions: 1) In the majority of patients with metastatic MTC, tumor sites can be visualized using octreotide scintigraphy, although this technique is insensitive in detecting liver metastases or intrathyroidal tumor; 2) The visualization of MTC during in vivo somatostatin receptor imaging correlates with the in vitro presence of somatostatin receptors; 3) The immunohistochemical presence of somatostatin in the tumor does not seem to influence the outcome of in vivo somatostatin receptor imaging; and 4) Higher serum calcitonin over carcino-embryonic antigen ratios in patients whose MTC is visualized during octreotide scintigraphy might imply that somatostatin receptors are present on more differentiated MTC."
2.	Neuroendocrine Tumors (Neuroendocrine Tumor) 06/01/2016 - "The human somatostatin receptor 3 (sst3) is expressed in about 50% of all neuroendocrine tumors and hence a promising target for multireceptor somatostatin analogs. "
3.	Autosomal Dominant Polycystic Kidney (ADPKD) 10/15/2014 - "Here, we demonstrate that, unlike the seven-span somatostatin receptor 3 or the leptin receptor that interacts with all subunits of the BBSome, the ADPKD protein polycystin-1 (PC1) interacts with BBS1, BBS4, BBS5 and BBS8, four of the seven components of the BBSome. "
4.	Neoplasm Metastasis (Metastasis) 06/01/1993 - "We have formed the following conclusions: 1) In the majority of patients with metastatic MTC, tumor sites can be visualized using octreotide scintigraphy, although this technique is insensitive in detecting liver metastases or intrathyroidal tumor; 2) The visualization of MTC during in vivo somatostatin receptor imaging correlates with the in vitro presence of somatostatin receptors; 3) The immunohistochemical presence of somatostatin in the tumor does not seem to influence the outcome of in vivo somatostatin receptor imaging; and 4) Higher serum calcitonin over carcino-embryonic antigen ratios in patients whose MTC is visualized during octreotide scintigraphy might imply that somatostatin receptors are present on more differentiated MTC."
5.	Gallbladder Neoplasms (Gallbladder Cancer) 01/01/2013 - "Somatostatin receptors 3, 4 and 5 play important roles in gallbladder cancer."

Related Drugs and Biologics

1.	Somatostatin (Somatotropin Release-Inhibiting Factor)
2.	Leptin Receptors
3.	Somatostatin Receptors (Somatostatin Receptor)
4.	Octreotide (Sandostatin)
5.	Messenger RNA (mRNA)
6.	Serotonin Receptors
7.	Proteins (Proteins, Gene)
8.	Calcitonin (Calcitonin, Eel)
9.	Antigens