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CB 1093
a Vitamin D analog; structure given in first source
Also Known As:
20-epi-22-ethoxy-23-yne-24,26,27-trihomo-1,25-dihydroxyvitamin D3; CB-1093
Networked:
3
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Polycyclic Compounds: 6
Fused-Ring Compounds
Steroids: 70059
Secosteroids: 22
Vitamin D: 33265
Cholecalciferol: 4786
Hydroxycholecalciferols: 25
Dihydroxycholecalciferols: 2
Calcitriol: 5322
CB 1093: 3
Cholestanes
Sterols: 2245
Cholecalciferol: 4786
Hydroxycholecalciferols: 25
Dihydroxycholecalciferols: 2
Calcitriol: 5322
CB 1093: 3
Cholestenes
Cholecalciferol: 4786
Hydroxycholecalciferols: 25
Dihydroxycholecalciferols: 2
Calcitriol: 5322
CB 1093: 3
Lipids: 114793
Membrane Lipids: 1591
Sterols: 2245
Cholecalciferol: 4786
Hydroxycholecalciferols: 25
Dihydroxycholecalciferols: 2
Calcitriol: 5322
CB 1093: 3
Related Diseases
1.
Neoplasms (Cancer)
09/01/1998 - "
The combination of CB 1093 + Taxol + CDDP was most potent, inhibiting tumor weights by nearly 83% compared to control tumors and producing extensive necrosis of the remaining tumor mass.
"
10/01/1999 - "
The hormonally active form of vitamin D3, 1,25-dihydroxyvitamin D3, and its two analogues, EB 1089 and CB 1093, are novel putative anticancer agents with an interesting profile of induction of growth inhibition, differentiation, and apoptosis in tumor cells.
"
02/27/1996 - "
These findings, together with the fact that the therapies currently available for glioma are only palliative, suggest that 1 alpha,25(OH)2D3 analogues such as KH 1060, EB 1089 or CB 1093, alone or in combination with other therapeutic approaches, could be of potential interest in the treatment of brain glial tumors.
"
2.
Necrosis
09/01/1998 - "
The combination of CB 1093 + Taxol + CDDP was most potent, inhibiting tumor weights by nearly 83% compared to control tumors and producing extensive necrosis of the remaining tumor mass.
"
3.
Glioma (Gliomas)
02/27/1996 - "
These findings, together with the fact that the therapies currently available for glioma are only palliative, suggest that 1 alpha,25(OH)2D3 analogues such as KH 1060, EB 1089 or CB 1093, alone or in combination with other therapeutic approaches, could be of potential interest in the treatment of brain glial tumors.
"
Related Drugs and Biologics
1.
seocalcitol
2.
Paclitaxel (Taxol)
3.
Cholecalciferol (Vitamin D3)
4.
Calcitriol (Calcijex)
5.
Antineoplastic Agents (Antineoplastics)
6.
KH 1060
7.
hydroxide ion
Related Therapies and Procedures
1.
Therapeutics