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4- (10- (4- iodophenyl)decyl)benzenepropanoic acid
Also Known As:
PHIPA 3-10
Networked:
2
relevant articles (
0
outcomes,
1
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Carboxylic Acids: 973
Carbocyclic Acids
Phenylpropionates
4-(10-(4-iodophenyl)decyl)benzenepropanoic acid: 2
Related Diseases
1.
Cardiomyopathies (Cardiomyopathy)
12/01/1997 - "
PHIPA 3-10 [13-(4'-iodophenyl)-3-(p-phenylene)tridecanoic acid] is a p-phenylene-bridged, radioiodinated omega-phenyl fatty acid that has recently been developed to study coronary artery disease or cardiomyopathies.
"
2.
Coronary Artery Disease (Coronary Atherosclerosis)
12/01/1997 - "
PHIPA 3-10 [13-(4'-iodophenyl)-3-(p-phenylene)tridecanoic acid] is a p-phenylene-bridged, radioiodinated omega-phenyl fatty acid that has recently been developed to study coronary artery disease or cardiomyopathies.
"
3.
Cicatrix (Scar)
12/01/1996 - "
The differences of biodistribution in viable myocardium and scars indicate that not only perfusion but also the metabolic state of the myocardium can be evaluated with radioiodinated PHIPA 3-10.
"
12/01/1996 - "
In viable myocardium, there was a significantly higher accumulation of [131I]PHIPA 3-10 compared to 99mTc-sestamibi (mean 5.9 x 10(-3) versus 2.7 x 10(-3)%ID/g),whereas in scars the uptake of both tracers was comparable (1.2 x 10(-3) versus 1.4 x 10(-3)%ID/g).
"
12/01/1996 - "
In the preoperative scans, a mismatch of fatty acid uptake and perfusion ([123I]PHIPA 3-10 > flow) was observed which indicated residual viable myocardium, while a matched defect was associated with scar.
"
Related Drugs and Biologics
1.
Fatty Acids (Saturated Fatty Acids)
2.
Acids
3.
Technetium Tc 99m Sestamibi (Cardiolite)