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X 910279
a malononitrilamide
Also Known As:
MNA 279; MNA-279; X-910279; X91 0279
Networked:
4
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Nitriles: 227
X 910279: 4
Related Diseases
1.
Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental)
08/01/1997 - "
Malononitrilamides (MNA 279 and MNA 715) have therapeutic activity in acute and chronic relapsing experimental allergic encephalomyelitis (EAE).
"
01/01/1997 - "
Therapeutic activity of malononitrilamides (MNA 279 and MNA 715) on acute and chronic, relapsing, experimental, allergic encephalomyelitis (EAE).
"
2.
Multiple Sclerosis
01/01/1997 - "
All these results qualify both MNA 279 and MNA 715 as powerful immunosuppressants with therapeutic potential in human multiple sclerosis (MS).
"
3.
Systemic Lupus Erythematosus (Libman-Sacks Disease)
08/01/1997 - "
Prevention of the development of murine systemic lupus erythematosus (SLE)-like diseases by the malononitrilamides MNA 279 and MNA 715.
"
4.
Graft vs Host Disease (Graft-Versus-Host Disease)
01/01/1997 - "
The new immunosuppressants, the malononitrilamides MNA 279 and MNA 715, inhibit various graft-vs.-host diseases (GvHD) in rodents.
"
Related Drugs and Biologics
1.
2- cyano- 3- hydroxy- N- (4- (trifluoromethyl)phenyl)- 2- hepten- 6- ynamide
2.
Immunosuppressive Agents (Immunosuppressants)