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gadolinium-1-(p-butylbenzyl)-DTPA

a hepatobiliary MRI contrast agent

Also Known As:

Gd-1-(p-butylbenzyl)-DTPA; MS 264; MS-264

Networked: 4 relevant articles (0 outcomes, 3 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133

Experts

1.	Gao, Cong: 1 article (01/2016)
2.	Huang, Qingmei: 1 article (01/2016)
3.	Liang, Junyan: 1 article (01/2016)
4.	Long, Youming: 1 article (01/2016)
5.	Tao, Ailin: 1 article (01/2016)
6.	Wu, Linzhan: 1 article (01/2016)
7.	Xu, Huiming: 1 article (01/2016)
8.	Yang, Xinguang: 1 article (01/2016)
9.	Zhong, Rong: 1 article (01/2016)
10.	Zhuang, Shunzhi: 1 article (01/2016)

Related Diseases

1.	Optic Neuritis (Retrobulbar Neuritis) 11/01/2002 - "The aim of the work was to study immunogenetic peculiarities of optic neuritis in children with MS. Using PCR-SSP technique genomic typing was performed on HLA DRB1 gene (chromosome 6p21) of 56 unrelated children with ON registered at least once in clinically verified MS. 264 adult MS patients and 328 healthy controls from the same stratum of population were also genotyped. "
2.	Multiple Sclerosis 03/15/2015 - "Previous studies suggested that serum neuron specific enolase (NSE) may be a biomarker associated with progression in MS. We measured serum NSE levels in 385 patients with multiple sclerosis (MS) (264 with relapsing-remitting (RR) MS, 86 with secondary progressive (SP) MS, and 35 with primary progressive (PP) MS), and compared levels between disease courses, between users and non-users of immunomodulatory treatment, and between patients with worsening or stable disability at one year follow-up (available in 161 patients). "
3.	Liver Neoplasms (Liver Cancer) 04/01/1996 - "In this animal study, MS-264 proved to be useful in detection and characterization of primary liver cancers."
4.	Neuromyelitis Optica (Devic's Disease) 01/01/2016 - "We tested 904 subjects, including 188 patients with MS, 264 patients with neuromyelitis optica spectrum disorders (NMOSD), 209 patients with other inflammatory neurologic disease (OIND), 203 patients with other noninflammatory neurological disease (OND), and 40 healthy controls. "
5.	Neoplasms (Cancer) 04/01/1996 - "In seven rats with 66 HCC lesions, enhancements of different abdominal organs and tumors were compared on T1-weighted images after intravenous administration of Gd-DTPA (0.3 mmol/kg) and MS-264 (0.05 mmol/kg). " 04/01/1996 - "A new MR contrast agent, MS-264 (Gd(1RS)-1-(p-butylbenzyl)-DTPA), was developed to achieve hepatobiliary specificity and its potential evaluated for detecting and characterizing liver tumors in rats with chemically induced hepatocellular carcinoma (HCC). "

Related Drugs and Biologics

1.	HLA-DRB1 Chains (HLA DRB1)
2.	Biomarkers (Surrogate Marker)
3.	Phosphopyruvate Hydratase (Enolase)
4.	Gadolinium DTPA (Magnevist)
5.	Contrast Media

Related Therapies and Procedures

1.	Intravenous Administration