DPPE-PEG2000

dipalmitoylphosphatidylethanolamine with covalently bound poly(ethylene glycol) of MW 2000

Also Known As:

DPPE-PEG; DPPE-PEG3400; DPPE-PEG750; dipalmitoylphosphatidylethanolamine-polyethylene glycol

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

1.	Neoplasms (Cancer) 08/11/1997 - "Inclusion of DPPE-PEG-Mal and linkage of the Fab' fragment instead of intact antibody to PEG terminals allowed the liposomes to evade RES uptake and remain in the circulation for a long time, resulting in enhanced accumulation of the liposomes in the solid tumor. " 02/01/2019 - "Bufalin-Loaded CaP/DPPE-PEG-EGF Nanospheres: Preparation, Cellular Uptake, Distribution, and Anti-Tumor Effects."
2.	Rupture 01/01/2008 - "Relative to PEG-free preparations, vesicles containing DPPE-PEG (1) formed larger contact zones, (2) underwent adhesion and fusion processes more slowly (by two to four times) and (3) at high charge density were less susceptible to rupture upon contact. "
3.	Asthma (Bronchial Asthma) 02/15/2010 - "Because iNKT cells play a critical role in the development of AHR, the inhibition of iNKT activation by DPPE-PEG suggests a novel approach to treat iNKT cell-mediated diseases such as asthma."

1.	Liposomes (Liposome)
2.	Immunoglobulin Fab Fragments
3.	Epidermal Growth Factor (EGF)
4.	bufalin

1.	Nanospheres