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3-hydroxy-13-methyltetradecanoic acid

stimulates secretion of apolipoprotein E in hepatoma cells; structure in first source

Also Known As:

N 4909; N-4909

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Polycyclic Compounds: 6
- Macrocyclic Compounds: 15
  - Cyclic Peptides: 530
    - 3-hydroxy-13-methyltetradecanoic acid: 3
Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Cyclic Peptides: 530
    - 3-hydroxy-13-methyltetradecanoic acid: 3

Experts

1.	Hiramoto, S: 1 article (12/2000)
2.	Kawamura, K: 1 article (12/2000)
3.	Oshida, N: 1 article (12/2000)
4.	Shingai, A: 1 article (12/2000)
5.	Suguro, T: 1 article (12/2000)
6.	Suzuki, M: 1 article (12/2000)
7.	Yanai, M: 1 article (12/2000)
8.	Yasuda, O: 1 article (12/2000)

Related Diseases

1.

Hepatocellular Carcinoma (Hepatoma)

02/01/1999 - "The R configuration of 3-hydroxy-13-methyltetradecanoic acid was found to be important for stimulating the activity of apolipoprotein E secretion in human hepatoma Hep G2 cells."
02/01/1999 - "First total synthesis of N-4909 and its diastereomer; a stimulant of apolipoprotein E secretion in human hepatoma Hep G2 cells."
09/01/1996 - "Stimulation of apolipoprotein E secretion in human hepatoma Hep G2 cells by a cyclic acylpeptide, N-4909."
12/01/2000 - "Analogs of N-4909 (1), which had a stimulating activity for apolipoprotein E (apo E) secretion in Human hepatoma Hep G2 cells, were prepared and their activities examined. "

Related Drugs and Biologics

1.	Apolipoproteins
2.	Apolipoproteins E (ApoE)