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reverse D amino acid mouse proline-glycine-proline peptide

mimics CDR3-D1 domain of CD4; tridecapeptide derived from CD4(86-94)

Also Known As:

rD-mPGPtide

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Oligopeptides: 519
    - reverse D amino acid mouse proline-glycine-proline peptide: 2

Related Diseases

1.	Wasting Syndrome (Wasting Disease) 01/01/1999 - "After treatment with the rD-mPGPtide, a striking improvement of diarrhea and acute wasting disease was observed with decreased mortality. "
2.	Inflammation (Inflammations) 01/01/1999 - "i.v. administration of the rD-mPGPtide but not control scrambled peptide could suppress severe inflammation in the chronic colitis mouse model. "
3.	Graft vs Host Disease (Graft-Versus-Host Disease) 10/15/1996 - "In this current report, we have evaluated the potential of rD-mPGPtide for suppressing the development of graft-versus-host disease (GVHD) in an irradiated major histocompatibility complex (MHC)-haploidentical murine bone marrow transplantation (BMT) model [(B6 x DBA/2)F1-->(B6 x CBA)F1 (950 cGy)]. "
4.	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 10/15/1996 - "In addition, rD-mPGPtide proved to be a potent inhibitor in vivo of CD4+ T-cell-mediated experimental allergic encephalomyelitis disease in the SJL mouse model. "
5.	Diarrhea 01/01/1999 - "After treatment with the rD-mPGPtide, a striking improvement of diarrhea and acute wasting disease was observed with decreased mortality. "

Related Drugs and Biologics

1.	Therapeutic Uses
2.	Complementarity Determining Regions (Complementarity Determining Region)
3.	Sulfonic Acids
4.	Peptides (Polypeptides)
5.	sym-trinitrobenzene

Related Therapies and Procedures

1.	Bone Marrow Transplantation (Transplantation, Bone Marrow)
2.	Aftercare (After-Treatment)