HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

formamidase

mediates the highly specific hydrolysis of formamide to produce formate and ammonium

Networked: 6 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Hydrolases: 2166
    - Amidohydrolases: 43
      - formamidase: 6

Related Diseases

1.	Tuberculosis (Tuberculoses) 01/01/1967 - " the identification tests studied, the formamidase test was found very useful for differentiating saprophytic mycobacteria from the other non-tuberculosis mycobacteria, particularly the rapid growers. " 01/01/1967 - "The third study in a series on the prevalence of non-tuberculosis mycobacteria in Africa is devoted to the investigation of the formamidase activity of 288 cultures of mycobacteria, already typed by a battery of standard tests as pathogenic or atypical (184 strains) and saprophytic (104 strains). "
2.	Infections 10/12/2022 - "Moreover, formamidase was important for fungal survival inside macrophages, as fungal recovery after macrophage infection was lower in AsFmd compared to wild-type (WT) strain. " 01/01/2022 - "Furthermore, we show that the B. abortus enzyme (Bab2_0247, Ba-BrbF) is also an 2-amino-5-formylamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate formamidase, and that the bab2_0247 mutant is a RF auxotroph exhibiting a lower level of intracellular infection than the wildtype strain. "
3.	Neoplasms (Cancer) 11/30/2022 - "Thus, Trp 2,3-dioxygenase (TDO2), indoleamine 2,3-dioxygenase 1 (IDO1), IDO2, N'-formylkynurenine formamidase (FAMID) and Kyn aminotransferase 1 (KAT1) are all up-regulated in many cancer types, whereas Kyn monooxygenase (KMO), kynureninase (KYNU), 2-amino-3-carboxymuconic acid-6-semialdehyde decarboxylase (ACMSD) and quinolinate phosphoribosyltransferase (QPRT) are up-regulated in a few, but down-regulated in many, cancers. "
4.	Aneuploidy (Aneuploid) 08/01/1978 - "The response of formamidase activity to change in gene dosage was measured in segmental aneuploids generated in the second, third, and X chromosomes. "

Related Drugs and Biologics

1.	Indoleamine-Pyrrole 2,3,-Dioxygenase (Indoleamine 2,3 Dioxygenase)
2.	Mixed Function Oxygenases (Monooxygenases)
3.	Enzymes
4.	Carboxy-Lyases
5.	Transaminases (Aminotransferases)
6.	nicotinate-nucleotide diphosphorylase (carboxylating)
7.	kynureninase
8.	N'-formylkynurenine