4''-epiacetylamino-4''-deoxyavermectin B1 (eprinomectin)

03/01/2013 - "The results of this series of controlled studies demonstrated high therapeutic efficacy and acceptability of eprinomectin ERI against pulmonary nematodes and a wide range of gastrointestinal parasitic infections, including inhibited gastrointestinal nematodes, in cattle."
03/01/2013 - "The therapeutic efficacy of eprinomectin in an extended-release injection (ERI) formulation was evaluated against induced infections of developing fourth-stage larval or adult gastrointestinal and pulmonary nematodes of cattle in a series of six studies under two identical protocols (three each for developing fourth-stage larvae or adults) conducted in the USA, Germany or the UK (two studies at each location, one per stage). "
03/01/2013 - "Therapeutic efficacy of eprinomectin extended-release injection against induced infections of developing (fourth-stage larvae) and adult nematode parasites of cattle."
04/28/2014 - "Efficacy of a single dose of a novel topical combination product containing eprinomectin to prevent heartworm infection in cats."
03/01/2013 - "The efficacy of eprinomectin in an extended-release injection (ERI) formulation was evaluated against infections with third-stage larvae or eggs of gastrointestinal and pulmonary nematodes in cattle under 120-day natural challenge conditions in a series of five studies conducted in the USA (three studies) and in Europe (two studies). "

04/01/1997 - "These studies showed eprinomectin to be effective against gastro-intestinal nematode infections and safe for use in dairy cattle under natural field conditions."
06/01/1997 - "Eprinomectin is a safe and effective nematocide against naturally acquired nematode infections in cattle when administered at a dosage of 500 micrograms/kg. Milk and meat withholding is not necessary when using this product."
02/01/1997 - "Two controlled studies involving 24 cattle were conducted in New Zealand to determine the efficacy of a topical, non-flammable formulation of eprinomectin against induced and naturally acquired nematode infections. "
03/10/2003 - "Efficacy of eprinomectin pour-on against gastrointestinal nematode infections in sheep."
11/10/2004 - "Impact of eprinomectin on grazing behaviour and performance in dairy cattle with sub-clinical gastrointestinal nematode infections under continuous stocking management."

11/01/1997 - "To determine whether eprinomectin was effective against mange caused by Chorioptes bovis and Sarcoptes bovis in cattle. "
10/01/2005 - "Results of this trial indicated that eprinomectin was partially effective in the treatment of psoroptic mange in rabbits."
12/01/2005 - "A randomized block design study was conducted to confirm the efficacy of topical eprinomectin against naturally acquired Chorioptes bovis mite infestations. "
10/01/2008 - "The purpose of this prospective, double-blinded, placebo-controlled clinical trial was to investigate the efficacy of topical eprinomectin for the treatment of psoroptic mange infestation in horses. "
11/01/1997 - "Efficacy of eprinomectin against mange mites in cattle."

10/01/2013 - "A trial was conducted on 12 buffaloes naturally infested with Rhipicephalus (Boophilus) microplus to evaluate the efficacy of eprinomectin pour-on at a dose of 0.5 mg/kg body weight. "
10/01/2009 - "A study was carried out to determine the efficacy of topical eprinomectin against nymphal infestation of Otobius megnini in cattle, where a group of 14 individuals were treated with a dose of 0.5mg/per kg of body weight applied on the dorsal midline, and a group of 14 individuals remained as control. "
11/16/2005 - "A study of the tissue depletion of eprinomectin (EPR) subcutaneously administered to cattle at a dose of 500 mg per kg of body weight was carried out. "
11/01/2000 - "In each study, calves were randomly assigned to one untreated group and up to four test groups, which were treated with eprinomectin at 500 microg/kg body weight at weekly intervals before single bolus challenge. "
12/15/1997 - "In two dose titration trials, eprinomectin dosages of 125 to 750 mcg/kg body weight applied topically were compared to untreated controls. "

04/28/2014 - "The efficacy of a novel topical combination formulation of fipronil, (S)-methoprene, eprinomectin and praziquantel against naturally acquired intestinal nematode and cestode infections in cats was evaluated in seven negative control, blinded studies. "
04/28/2014 - "Efficacy of a novel topical fipronil, (S)-methoprene, eprinomectin and praziquantel combination against naturally acquired intestinal nematode and cestode infections in cats."
04/28/2014 - "A novel topical combination product (BROADLINE(®), Merial) composed of fipronil, (S)-methoprene, eprinomectin and praziquantel was evaluated for safety and efficacy against nematode and cestode infections in domestic cats. "
04/28/2014 - "Efficacy against nematode and cestode infections and safety of a novel topical fipronil, (S)-methoprene, eprinomectin and praziquantel combination product in domestic cats under field conditions in Europe."
04/28/2014 - "The results of this series of controlled studies demonstrated high efficacy and excellent acceptability of the novel topical combination formulation of fipronil, (S)-methoprene, eprinomectin and praziquantel against a broad range of feline intestinal nematode and cestode infections."