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nigranoic acid

from stem of Schisandra sphaerandra; structure in first source

Also Known As:

3,4-secocycloarta-4(28),24(Z)-diene-3,26-dioic acid

Networked: 1 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Terpenes: 1461
    - Triterpenes: 2493
      - nigranoic acid: 1

Experts

1.	Feng, Tianda: 1 article (01/2015)
2.	Li, Chao: 1 article (01/2015)
3.	Li, Zhen: 1 article (01/2015)
4.	Liu, Yunhui: 1 article (01/2015)

Related Diseases

1.	Brain Ischemia (Cerebral Ischemia) 01/01/2015 - "Rats in the nigranoic acid group were administered with 1 mg/kg intragastric nigranoic acid 6 and 2 h before brain ischemia, respectively. " 01/01/2015 - "Protective effects of nigranoic acid on cerebral ischemia-reperfusion injury and its mechanism involving apoptotic signaling pathway." 01/01/2015 - "We can judge that nigranoic acid has a strong protective effect on rat cerebral ischemia-reperfusion injury, and acts by downregulating nerve cell apoptosis by preventing the overactivation of PARP and AIF nuclear translocation." 01/01/2015 - "The goal of this study was to assess the expression of poly ADP-ribose polymerase (PARP) and apoptosis-inducing factor (AIF) in the hippocampal CA1 region, and to find out whether nigranoic acid treatment exhibits protective effects on brain through PARP/AIF signaling pathway in cerebral ischemia-reperfusion animal model. "
2.	Reperfusion Injury 01/01/2015 - "Protective effects of nigranoic acid on cerebral ischemia-reperfusion injury and its mechanism involving apoptotic signaling pathway." 01/01/2015 - "We can judge that nigranoic acid has a strong protective effect on rat cerebral ischemia-reperfusion injury, and acts by downregulating nerve cell apoptosis by preventing the overactivation of PARP and AIF nuclear translocation."
3.	Ischemia 01/01/2015 - "Rats were randomly divided into three groups: Sham-surgery, ischemia-reperfusion, and nigranoic acid-treated. "

Related Drugs and Biologics

1.	Apoptosis Inducing Factor
2.	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)
3.	salicylhydroxamic acid (SHAM)