cytohesin-1

Also Known As:

PSCD1 protein, human; Pscd1 protein, mouse; cytohesin 1, mouse; cytohesin-1, human; pleckstrin homology, Sec7 and coiled-coil domains 1(cytohesin 1) protein, human; pleckstrin homology, Sec7 and coiled-coil domains 1, mouse

Networked: 6 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Intracellular Signaling Peptides and Proteins: 32
    - GTP-Binding Protein Regulators
      - Guanine Nucleotide Exchange Factors: 592
        cytohesin-1: 6
- Peptides: 82426
  - Intracellular Signaling Peptides and Proteins: 32
    - GTP-Binding Protein Regulators
      - Guanine Nucleotide Exchange Factors: 592
        cytohesin-1: 6

Experts

1.	Antoine, Jean-Christophe: 1 article (01/2021)
2.	Camdessanché, Jean-Philippe: 1 article (01/2021)
3.	Ferraud, Karine: 1 article (01/2021)
4.	Moritz, Christian P: 1 article (01/2021)
5.	Stoevesandt, Oda: 1 article (01/2021)
6.	Tholance, Yannick: 1 article (01/2021)
7.	Kato, Minoru: 1 article (10/2013)
8.	Kawahara, Katsumasa: 1 article (10/2013)
9.	Kotera, Jun: 1 article (10/2013)
10.	Miyamoto, Yuki: 1 article (10/2013)

Related Diseases

1.	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 08/29/2023 - "In this study, we investigated the prognostic role and functional significance of cytohesin-1 (CYTH1) in acute myeloid leukemia (AML). " 08/29/2023 - "Targeting cytohesin-1 suppresses acute myeloid leukemia progression and overcomes resistance to ABT-199."
2.	Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP) 01/01/2021 - "There are potential novel CIDP-specific autoantigens such as the myelination- or axo-glial structure-related proteins actin-related protein 2/3 complex subunit 1B, band 4.1-like protein 2, cadherin-15, cytohesin-1, epidermal growth factor receptor, ezrin, and radixin. "
3.	Prostatic Neoplasms (Prostate Cancer) 07/01/2011 - "In conclusion, the interference of siRNA with cytohesin-1 leads to reduced IGFR signaling in prostate cancer; therefore, CYTH-1 might serve as a new molecular target for the treatment of prostate cancer." 07/01/2011 - "Inhibition of cytohesin-1 by siRNA leads to reduced IGFR signaling in prostate cancer." 07/01/2011 - "To explore how cytohesin-1 (CYTH-1) small interfering RNA (siRNA) influences the insulin-like growth factor receptor (IGFR)-associated signal transduction in prostate cancer, we transfected human prostate cancer PC-3 cell lines with liposome-encapsulated CYTH-1 siRNA in serum-free medium and exposed the cells to 100 nM IGF-1. "
4.	Peripheral Nervous System Diseases (PNS Diseases) 10/01/2013 - "These results suggest that cytohesin-1 may be a candidate for the basis of a therapy for peripheral neuropathies through its enhancement of myelin thickness. "
5.	Neoplasms (Cancer) 08/01/2007 - "Cytohesin-1 had been identified as a regulator of beta2 integrin inside-out regulation in immune cells and was subsequently shown to be involved in mitogen-associated protein kinase signaling in tumor cell proliferation as well as in T-helper cell activation and differentiation. "

Related Drugs and Biologics

1.	Proteins (Proteins, Gene)
2.	ErbB Receptors (EGF Receptor)
3.	Actin-Related Protein 2-3 Complex (Arp2 3 Complex)
4.	Small Interfering RNA (siRNA)
5.	Guanine Nucleotide Exchange Factors (Guanine Nucleotide Exchange Factor)
6.	CD18 Antigens
7.	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)
8.	Somatomedin Receptors (Somatomedin Receptor)
9.	Integrins
10.	Protein Kinases (Protein Kinase)

Related Therapies and Procedures

1.	Therapeutics