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trypanopain Tb

isolated from Trypanosoma brucei brucei

Also Known As:

brucipain, Trypanosoma brucei; trypanopain-Tb

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Hydrolases: 2166
    - Peptide Hydrolases: 23957
      - Cysteine Proteases: 1964
        Cysteine Endopeptidases: 4
        trypanopain Tb: 2
      - Endopeptidases: 633
        Cysteine Endopeptidases: 4
        trypanopain Tb: 2

Experts

1.	Asati, Vivek: 1 article (08/2015)
2.	Bharti, Sanjay Kumar: 1 article (08/2015)
3.	Mahapatra, Debarshi Kar: 1 article (08/2015)
4.	Chen, X: 1 article (08/2000)
5.	Cheng, M: 1 article (08/2000)
6.	Coetzer, T H: 1 article (08/2000)
7.	Cohen, F E: 1 article (08/2000)
8.	Flaherty, T M: 1 article (08/2000)
9.	Hua, H: 1 article (08/2000)
10.	Kenyon, G L: 1 article (08/2000)

Related Diseases

1.	Trypanosomiasis 08/01/2000 - "brucei in cell culture and in a murine trypanosomiasis model, and investigated their ability to inhibit trypanopain-Tb, the major cysteine proteinase of T. "
2.	Hemolysis 08/28/2015 - "Several natural and (semi) synthetic chalcones deserve the credit of being potential anti-infective candidates that inhibit various parasitic, malarial, bacterial, viral, and fungal targets like cruzain-1/2, trypanopain-Tb, trans-sialidase, glyceraldehyde-3-phosphate dehydrogenase (GAPDH), fumarate reductase, falcipain-1/2, β-hematin, topoisomerase-II, plasmepsin-II, lactate dehydrogenase, protein kinases (Pfmrk and PfPK5), and sorbitol-induced hemolysis, DEN-1 NS3, H1N1, HIV (Integrase/Protease), protein tyrosine phosphatase A/B (Ptp-A/B), FtsZ, FAS-II, lactate/isocitrate dehydrogenase, NorA efflux pump, DNA gyrase, fatty acid synthase, chitin synthase, and β-(1,3)-glucan synthase. "

Related Drugs and Biologics

1.	Fatty Acid Synthases (Fatty Acid Synthase)
2.	Cysteine Proteases (Cysteine Protease)
3.	Chalcones
4.	DNA Gyrase
5.	HIV Integrase
6.	Lactic Acid (Lactate)
7.	Protein Tyrosine Phosphatases
8.	Succinate Dehydrogenase (Fumarate Reductase)
9.	Sorbitol (Yal)
10.	Protein Kinases (Protein Kinase)