azauracil

minor descriptor (64-72); major descriptor (73-86); on line search URACIL (66-74); URACIL/AA (75-86); INDEX MEDICUS search URACIL (64-72); AZAURACIL (73-86)

Also Known As:

Networked: 14 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Chen, Apeng: 1 article (05/2012)
2.	Gross, David S: 1 article (05/2012)
3.	Jeon, Jeong Ok: 1 article (05/2012)
4.	Kim, Sunyoung: 1 article (05/2012)
5.	Kremer, Selena B: 1 article (05/2012)
6.	Moustafa, Yara W: 1 article (05/2012)
7.	Zhao, Jing: 1 article (05/2012)
8.	Balakrishnan, S K: 1 article (04/2008)
9.	Gross, D S: 1 article (04/2008)
10.	Kashlev, Mikhail: 1 article (04/2006)

Related Diseases

1.	Pulmonary Eosinophilia (Eosinophilic Pneumonia) 11/01/2000 - "This study describes the identification of R146225, a novel six-substituted azauracil derivative, as a potent, orally active inhibitor of IL-5 biosynthesis, capable of reducing pulmonary eosinophilia in mice. "
2.	Neoplasms (Cancer) 11/01/1960 - "Excretion of 6-azauracil riboside in cancer patients." 01/01/1973 - "[Influence of cyclophosphamide, ribo-azauracil and mercaleukin pretreatment on experimental metastasizing in a syngenic tumor-host system. " 02/13/1993 - "Alanine-glyoxylate aminotransferase activity and D-3-aminoisobutyrate-pyruvate aminotransferase activities were inactivated competitively with respect to beta-alanine by 5-fluorouracil and 6-azauracil, which are chemotherapeutic reagents used to cancer. "
3.	Hypersensitivity (Allergy) 05/01/2012 - "Suggestive of a more general role, ewe mutations confer hypersensitivity to the anti-elongation drug 6-azauracil (6-AU) and one of them-med21-impairs Pol II processivity on a GAL1-regulated reporter gene. " 04/24/2008 - "p53 levels comparable to those found in induced mammalian cells confer synthetic sickness or lethality in combination with deletions in genes encoding transcription elongation factors; p53 likewise confers hypersensitivity to the anti-elongation drug 6-azauracil. " 04/01/2006 - "Mutations in the Saccharomyces cerevisiae RPB1 gene conferring hypersensitivity to 6-azauracil."
4.	Wiskott-Aldrich Syndrome 03/07/2003 - "suppression of 6-azauracil sensitivity, induction of the IMD2 gene, and suppression of temperature sensitivity of spt4 null mutant)." 03/07/2003 - "6-Azauracil also induced IMD2 gene expression in both these mutant strains and the wild type. " 10/01/2002 - "In contrast, the resistance of paf1 Delta cells to the transcription elongation inhibitors 6-azauracil and mycophenolic acid correlates with its ability to derepress the IMD2 transcript. "
5.	Carcinogenesis 12/01/1977 - "Rates of tumorigenesis exceeded 95% for 0.5 mM solutions of either pyrogallol or 6-azauracil solutions in the presence of l mM O2. " 12/01/1977 - "Aqueous solutions of molecular oxygen, per se, or in combination with either pyrogallol or 6-azauracil increased tumorigenesis in Nicotiana suaveolens X Nicotiana langsdorffii seedlings relative to control seedlings. "

Related Drugs and Biologics

1.	Interleukin-5 (Interleukin 5)
2.	Fluorouracil (Carac)
3.	Cyclophosphamide (Cytoxan)
4.	Mercaptopurine (6 Mercaptopurine)
5.	beta-Alanine
6.	Thiotepa (Triethylenethiophosphoramide)
7.	Sulfur
8.	Pyrogallol
9.	Proteins (Proteins, Gene)
10.	Oxygen (Dioxygen)

Related Therapies and Procedures

1.	Therapeutics