azotomycin

minor descriptor (73-85); on-line & Index Medicus search AZO COMPOUNDS (73-85); RN given refers to all (L)-isomer

Also Known As:

NCS 56654; NCS-56654; azotomycin, monosodium salt; azotomycin, sodium salt; diazomycin B; duazomycin B

Networked: 4 relevant articles (0 outcomes, 1 trials/studies)

1.	Sarcoma (Soft Tissue Sarcoma) 12/01/1977 - "Phase II study of azotomycin in sarcomas."
2.	Neoplasms (Cancer) 06/01/1979 - "A renewed interest in these agents has been triggered by the remarkable activity of DON and azotomycin against human tumor lines implanted into nude mice. " 01/01/1980 - "DON (6-diazo-5-oxo-L-norleucine) and azotomycin are glutamine antagonists that were tested in human malignancies in the 1950s. " 08/01/1979 - "The chemotherapeutic effects of 6-diazo-5-oxo-L-norleucine (DON) and N-[N-gamma-glutamyl-6-diazo-5-oxo-norleucinyl]6-diazo-5-oxo-norleucine (azotomycin) were evaluated in a spectrum of transplantable experimental tumor systems including xenografts of human tumors in athymic mice. "
3.	Colorectal Neoplasms (Colorectal Cancer) 01/01/1980 - "Azotomycin demonstrated significant activity in colorectal cancer. "