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BM 16.2224 (BM 24)

a dibenz(b,e)oxepine derivative; inhibits secreted phospholipase A2 (sPLA2)

Also Known As:

BM 24; BM 162224; BM-16.2224; BM-24; BM24

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 3-Ring Heterocyclic Compounds
    - Dibenzoxepins
      - BM 16.2224: 3

Experts

1.	Doi, Hiroshi: 1 article (04/2020)
2.	Doi, Katsumi: 1 article (04/2020)
3.	Hyodo, Tomoko: 1 article (04/2020)
4.	Ishii, Kazunari: 1 article (04/2020)
5.	Kashiwagi, Nobuo: 1 article (04/2020)
6.	Kitano, Mutsukazu: 1 article (04/2020)
7.	Kozuka, Takenori: 1 article (04/2020)
8.	Nakanishi, Katsuyuki: 1 article (04/2020)
9.	Suzuki, Ayako: 1 article (04/2020)
10.	Tsurusaki, Masakatsu: 1 article (04/2020)

Related Diseases

1.	Nevus (Nevi) 06/01/1988 - "While S-100 protein was present in nevus cells at the epidermodermal junction and at all levels of the dermis, the melanoma-directed monoclonal antibodies BM 24-2, NKI/C-3, Mel-1, and Mel-2 reacted most prominently with the superficial (A-type) nevus cells; the B- and C-type cells being negative in these cells. "
2.	Muscular Diseases (Myopathy) 08/05/2023 - "Among the patients, 33 had Bethlem myopathy (BM), 24 had Ullrich congenital muscular dystrophy (UCMD), 7 had an intermediate phenotype (INTM), and five had myosclerosis myopathy (MM). "
3.	Melanoma (Melanoma, Malignant) 06/01/1988 - "While S-100 protein was present in nevus cells at the epidermodermal junction and at all levels of the dermis, the melanoma-directed monoclonal antibodies BM 24-2, NKI/C-3, Mel-1, and Mel-2 reacted most prominently with the superficial (A-type) nevus cells; the B- and C-type cells being negative in these cells. "
4.	Squamous Cell Carcinoma of Head and Neck 04/01/2020 - "Among 772 patients with HNSCC diagnosed at our hospital over 9 years, 30 patients (3.9%) had clinical evidence of BM (24 men and 6 women; mean age: 63 years). "
5.	Scleroatonic muscular dystrophy 08/05/2023 - "Among the patients, 33 had Bethlem myopathy (BM), 24 had Ullrich congenital muscular dystrophy (UCMD), 7 had an intermediate phenotype (INTM), and five had myosclerosis myopathy (MM). "

Related Drugs and Biologics

1.	S100 Proteins (S 100 Protein)
2.	Monoclonal Antibodies