creatinol phosphate

minor descriptor (75-85); on-line & Index Medicus search CREATINE/AA (75-85); RN given refers to parent cpd

Also Known As:

Aplodan; N-(2-hydroxyethyl)-N-methylguanidine dihydrogen phosphate; creatinol phosphate, magnesium salt (2:1); creatinol-O-phosphate; creatinolfosfat

Networked: 13 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amidines: 14
  - Guanidines: 29
    - Creatine: 3124
      - creatinol phosphate: 13
Amino Acids, Peptides, and Proteins: 1
- Amino Acids: 30675
  - Creatine: 3124
    - creatinol phosphate: 13

Related Diseases

1.	Hypoxia (Hypoxemia) 01/01/1984 - "Action of creatinol-O-phosphate on the contractility changes evoked by hypoxia and ischemia in rat isolated heart." 01/01/1984 - "When creatinol-O-phosphate was present during hypoxia, in the physiological solution, the recovery of the contraction after reoxygenation (in the absence of the drug) was improved in a dose-dependent manner. " 01/01/1984 - "The effect of creatinol-O-phosphate (N-methyl-N-(beta-hydroxyethyl)guanidine O-phosphate, creatinolfosfate, Aplodan) pretreatment has been studied on the recovery of contractility of rat isolated heart after hypoxia or ischemia. "
2.	Myocardial Infarction 01/01/1979 - "It is concluded that, due to its protective action against cardionecrosis, creatinol O-phosphate has great potential value in patients with myocardial infarction in whom the extent of the infarct size may be limited by an action on the jeopardized area." 01/01/1979 - "Effects of creatinol O-phosphate on serum enzymes in acute myocardial infarction." 01/01/1979 - "N-Methyl-N-(beta-hydroxyethyl) guanidine O-phosphate (creatinol O-phosphate, COP) was checked on patients suffering from inadequate coronary circulation (12 patients had a recent myocardial infarction and 13 were suffering from angina pectoris) versus a reference substance (solvent of COP) in a double blind study. "
3.	Heart Diseases (Heart Disease) 11/17/1972 - "[Clinical study on the effects of creatinol-O-phosphate in patients with heart diseases under digitalis treatment]." 09/01/1971 - "[Clinical effects of creatinol-O-phosphate in patients with heart diseases]." 06/01/1971 - "[Clinical results of using of creatinol-O-phosphate in heart diseases. "
4.	Atrioventricular Block 06/01/1971 - "[Effect of creatinol-O-phosphate on atrioventricular block induced by high doses of l-adrenaline in the isolated guinea-pig heart]."
5.	Myocardial Ischemia (Ischemic Heart Diseases) 01/01/1979 - "Activity of creatinol O-phosphate on persistent ventricular premature beats in ischemic heart disease. " 01/01/1979 - "In a double-blind investigation N-methyl-N-(beta-hydroxyethyl) guanidine O-phosphate (creatinol O-phosphate, COP) was checked versus a reference substance (solvent of COP) on volunteers affected by ischemic heart disease with persistent ventricular premature beats (VPB). "

Related Drugs and Biologics

1.	Solutions
2.	Guanidine (Guanidine Nitrate)
3.	Phosphates (Orthophosphate)
4.	Solvents
5.	creatinol phosphate
6.	Salts
7.	Epinephrine (Adrenaline)
8.	Enzymes
9.	Cardioplegic Solutions
10.	phosphoryl chloride