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iodouracil

minor descriptor (64-82); online & Index Medicus search URACIL/AA (64-82)

Networked: 13 relevant articles (0 outcomes, 3 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrimidines: 510
    - Pyrimidinones: 71
      - Uracil: 1493
        iodouracil: 13

Experts

1.	Pomper, Martin G: 3 articles (01/2012 - 01/2005)
2.	Foss, Catherine A: 2 articles (10/2008 - 01/2005)
3.	Beck, Graham: 1 article (01/2012)
4.	Jedynak, Bruno: 1 article (01/2012)
5.	Pullambhatla, Mrudula: 1 article (01/2012)
6.	Tessier, Jean: 1 article (01/2012)
7.	Wurthner, Jens U: 1 article (01/2012)
8.	Ambinder, Richard F: 1 article (10/2008)
9.	Chen, Jianmeng: 1 article (10/2008)
10.	Chong, Ja-Mun: 1 article (10/2008)

Related Diseases

1.	Infections 02/01/2004 - "The aim of our study was to compare uptake of the tk substrate 1-(2-fluoro-2-deoxy-beta-D-ribofuranosyl)-5-[*I]iodouracil (FIRU) labeled with 125I and the somatostatin analog 111In-DOTA-Tyr3-octreotate in several glioma cell lines after infection with Ad5.tk.sstr. " 01/01/2012 - "2'-Fluoro-2'-deoxy-1β-D-arabinofuranosyl-5-[(125)I]iodouracil ([(125)I]FIAU), a substrate for the thymidine kinase (TK) present in most bacteria, has been used as an imaging agent for single photon emission computed tomography (SPECT) in an experimental model of lung infection. " 04/16/1996 - "The thymidine analog fialuridine deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-iodouracil (FIAU) was toxic in trials for chronic hepatitis B infection. " 09/01/1984 - "FIAC [1-(2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl)-5-iodocytosine], FIAU [1-(2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl)-5-iodouracil], and FMAU [1-(2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl)-5-methyluracil] were evaluated for their efficacies in the treatment of genital infections with herpes simplex virus type 2 in guinea pigs. "
2.	Chronic Hepatitis B 04/16/1996 - "The thymidine analog fialuridine deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-iodouracil (FIAU) was toxic in trials for chronic hepatitis B infection. "
3.	Herpetic Keratitis 02/01/1964 - "[STUDIES ON THE EFFECT OF IODOURACIL-DESOXYRIBOSIDE (IUDR) ON THE EXPERIMENTAL HERPES SIMPLEX KERATITIS IN RABBITS]."
4.	Glioma (Gliomas) 02/01/2004 - "The aim of our study was to compare uptake of the tk substrate 1-(2-fluoro-2-deoxy-beta-D-ribofuranosyl)-5-[*I]iodouracil (FIRU) labeled with 125I and the somatostatin analog 111In-DOTA-Tyr3-octreotate in several glioma cell lines after infection with Ad5.tk.sstr. "
5.	Neoplasms (Cancer) 10/01/2008 - "In a mouse xenograft model, we had previously shown targeting of [(125)I]2'-fluoro-2'-deoxy-beta-D-5-iodouracil-arabinofuranoside ([(125)I]FIAU) to tumors engineered to express the Epstein-Barr virus thymidine kinase (EBV-TK). " 01/01/1984 - "Tumor uptake of radiolabelled pyrimidine bases and pyrimidine nucleosides in animal models--V. 6-[36Cl]chlorouracil, 6-[82Br]bromouracil and 6-[123I]iodouracil." 09/01/2003 - "Expression of a dihydrofolate reductase-herpes simplex virus 1 thymidine kinase fusion (DHFR-HSV1 TK) transgene in the hepatic tumors was monitored in individual animals using the tracer [(124)I]2'-fluoro-2'-deoxy-5-iodouracil-beta- d-arabinofuranoside (FIAU) and a small animal micro positron emission tomograph (microPET), while groups of rats were imaged using the tracer [(131)I]FIAU and a clinical gamma camera. " 01/01/1962 - "[The utilization of thymidine, bromodesoxyuridine and the free pyrimidine bases thymine, bromouracil and iodouracil in desoxyribonucleic acid synthes by ascites tumor cells in vitro]."

Related Drugs and Biologics

1.	fialuridine
2.	Thymidine
3.	Idoxuridine (Stoxil)
4.	Somatostatin (Somatotropin Release-Inhibiting Factor)
5.	Thymidine Kinase
6.	Thymine
7.	Bromouracil (5 Bromouracil)
8.	pyrimidine
9.	Anti-HIV Agents (AIDS Drugs)
10.	Tetrahydrofolate Dehydrogenase (Dihydrofolate Reductase)

Related Therapies and Procedures

1.	Gamma Cameras (Gamma Camera)