eritadenine

isolated from Lentinula edodes (Shiitake mushroom); inhibits S-adenosyl-L-homocysteine hydrolase activity

Also Known As:

6-amino-alpha,beta-dihydroxy-9H-purine-9-butanoic acid; eritadenine, (R-(R*,S*))-isomer; eritadenine, (S-(R*,R*))-isomer; eritadenine, (S-(R*,S*))-isomer; eritadenine, monosodium salt, (R-(R*,R*))-isomer; eritadenine, monosodium salt, (S-(R*,R*))-isomer; 9H-Purine-9-butanoic acid, 6-amino-alpha,beta-dihydroxy-, (alphaR,betaR)-

Networked: 7 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Purines: 651
      - Adenine: 2120
        eritadenine: 7

Experts

1.	Hong, Eui-Ju: 2 articles (12/2013 - 08/2013)
2.	Hwang, Inho: 2 articles (12/2013 - 08/2013)
3.	Jeung, Eui-Bae: 2 articles (12/2013 - 08/2013)
4.	Kim, Sun: 2 articles (12/2013 - 08/2013)
5.	Yang, Hyun: 2 articles (12/2013 - 08/2013)
6.	Morita, Tatsuya: 2 articles (11/2006 - 08/2006)
7.	Sugiyama, Kimio: 2 articles (11/2006 - 08/2006)
8.	Buzera, Ariel: 1 article (01/2022)
9.	Hammam, Ahmed R A: 1 article (01/2022)
10.	Ishara, Jackson: 1 article (01/2022)

Related Diseases

1.	Anxiety Disorders (Anxiety Disorder) 01/01/2023 - ""Eritadenine as a regulator of anxiety Disorders: An experimental and docking Approach"." 01/01/2023 - "This study explores eritadenine's potential as a bioactive substance for anxiety disorders in mice, employing behavioral tests, pentobarbital-sleep induction, and molecular docking. "
2.	Hyperhomocysteinemia 11/01/2006 - "The results confirm that GAA is a useful compound to induce experimental hyperhomocysteinemia and indicate that eritadenine can effectively counteract the hyperhomocysteinemic effect of GAA." 08/01/2013 - "edodes, including eritadenine may have beneficial effects on hyperhomocysteinemia and its therapeutic effects may be involved in the regulation of DNA methylation-related genes in mice." 11/01/2006 - "Dietary eritadenine suppresses guanidinoacetic Acid-induced hyperhomocysteinemia in rats." 08/01/2006 - "Suppression of methionine-induced hyperhomocysteinemia by dietary eritadenine in rats."
3.	Atherosclerotic Plaque (Atheroma) 12/01/2013 - "In addition, it was revealed that the formation of atherosclerotic plaques due to the HFD was also suppressed by eritadenine and L. "
4.	Obesity 01/01/2022 - "Numerous mushroom bioactive metabolites, including polysaccharides, eritadenine, lignin, chitosan, mevinolin, and astrakurkurone have been studied in life-threatening conditions and diseases such as diabetes, cardiovascular, hypertension, cancer, DNA damage, hypercholesterolemia, and obesity attempting to identify natural therapies. "
5.	Neoplasms (Cancer) 01/01/2022 - "Numerous mushroom bioactive metabolites, including polysaccharides, eritadenine, lignin, chitosan, mevinolin, and astrakurkurone have been studied in life-threatening conditions and diseases such as diabetes, cardiovascular, hypertension, cancer, DNA damage, hypercholesterolemia, and obesity attempting to identify natural therapies. "

Related Drugs and Biologics

1.	Pentobarbital (Nembutal)
2.	Chitosan
3.	Therapeutic Uses
4.	Polysaccharides (Glycans)
5.	Methionine (L-Methionine)
6.	Lovastatin (Mevacor)
7.	Lignin
8.	Choline (Choline Chloride)
9.	glycocyamine
10.	astrakurkurone

Related Therapies and Procedures

1.	Therapeutics