CB 30900

a nonpolyglutamated quinazoline antifolate

Also Known As:

CB-30900; CB30900; N-(N-(4-(N-((3,4-dihydro-2,7-dimethyl-4-oxo-6-quinazolinyl)methyl)-N-prop-2-ynylamino)-2-fluorobenzoyl)-L-gamma-glutamyl)-D-glutamic acid

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Oligopeptides: 519
    - Dipeptides: 945
      - CB 30900: 1
Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Quinazolines: 402
      - CB 30900: 1

Related Diseases

1.	Neoplasms (Cancer) 05/01/1996 - "CB30900 is a novel, potent thymidylate synthase inhibitor which can not be polyglutamated and may be active in cancers expressing low or defective folylpolyglutamate synthetase. "

Related Drugs and Biologics

1.	Thymidylate Synthase
2.	folylpolyglutamate synthetase