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TEI 7322
an anti-hypoxemic agent; structure given in first source
Also Known As:
2-allylamino-4-tert-butylamino-7-methyl-7H-pyrrolo(2,3-d)pyrimidine hydrochloride; TEI-7322
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Pyrimidines: 510
TEI 7322: 1
Related Diseases
1.
Lung Injury
12/04/1995 - "
In conclusion, (1) bleomycin-induced lung injury causes hypoxemia in rats, probably resulting from ventilation-perfusion inequality; thus this model may be useful for evaluating anti-hypoxemic agents; and (2) TEI-7322, as well as almitrine, showed anti-hypoxemic effects in this model with different properties from those of doxapram, possibly due to improvement of ventilation-perfusion inequality, indicating that TEI-7322 may be a potent candidate for the treatment of hypoxemia.
"
2.
Hypoxia (Hypoxemia)
12/04/1995 - "
Beneficial effects of a novel anti-hypoxemic agent, TEI-7322, on bleomycin-induced experimental hypoxemia in rats.
"
12/04/1995 - "
In conclusion, (1) bleomycin-induced lung injury causes hypoxemia in rats, probably resulting from ventilation-perfusion inequality; thus this model may be useful for evaluating anti-hypoxemic agents; and (2) TEI-7322, as well as almitrine, showed anti-hypoxemic effects in this model with different properties from those of doxapram, possibly due to improvement of ventilation-perfusion inequality, indicating that TEI-7322 may be a potent candidate for the treatment of hypoxemia.
"
Related Drugs and Biologics
1.
Almitrine (Vectarion)
2.
Doxapram (Doxapram Hydrochloride)
3.
Bleomycin (Blenoxane)