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methotrexate bisphosphonate

structure given in first source

Also Known As:

MTX-BP

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Organophosphorus Compounds: 300
  - Organophosphonates: 424
    - Diphosphonates: 11565
      - methotrexate bisphosphonate: 2
Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Pteridines: 147
      - Pterins: 160
        Aminopterin: 248
        Methotrexate: 24010
        methotrexate bisphosphonate: 2

Experts

1.	Pei, F-X: 1 article (01/2014)
2.	Song, Y-C: 1 article (01/2014)
3.	Yang, X-N: 1 article (01/2014)
4.	Zeng, J-C: 1 article (01/2014)
5.	Zhang, H: 1 article (01/2014)

Related Diseases

1.

Osteosarcoma (Osteogenic Sarcoma)

01/01/2014 - "A targeted antiosteosarcoma methotrexate-bisphosphonate conjugate induces apoptosis in human osteosarcoma MG-63 cells. "
01/01/2014 - "To investigate the effect of targeted antiosteosarcoma methotrexate-bisphosphonate conjugate on growth inhibition and apoptosis in human osteosarcoma MG-63 cells. "
01/01/2014 - "Targeted antiosteosarcoma methotrexate-bisphosphonate conjugate induces apoptosis of osteosarcoma cells in vitro."
01/01/1996 - "A methotrexate-bisphosphonate conjugate containing a peptide bond has been found to possess over five times greater antineoplastic activity against osteosarcoma in experimental animal models compared with methotrexate alone. "

Related Drugs and Biologics

1.	Peptides (Polypeptides)
2.	Methotrexate (Mexate)
3.	Antineoplastic Agents (Antineoplastics)