AMPA 1 glutamate receptor ionotropic

Also Known As:

glutamate receptor ionotropic, AMPA 1; AMPA receptor, GluR1 subunit; AMPA-selective glutamate receptor 1; AMPA-selective glutamate receptor 1, human; AMPA-selective glutamate receptor 1, mouse; AMPA-selective glutamate receptor 1, rat; GLUA1 protein, human; GRIA1 protein, human; GluA1 protein, rat; GluR-A subunit, mouse; Glur1 protein, mouse; Glur1 protein, rat; Gria1 protein, mouse; Gria1 protein, rat; glutamate receptor, ionotropic, AMPA 1, human; glutamate receptor, ionotropic, AMPA1 (alpha 1) protein, mouse; glutamate receptor, ionotropic, AMPA1 (alpha 1), rat; ionotropic glutamate receptor subunit GluR1

Networked: 3 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Garcia-Orad, Africa: 1 article (01/2017)
2.	Gutierrez-Camino, Angela: 1 article (01/2017)
3.	Iparraguirre, Leire: 1 article (01/2017)
4.	Lopez-Santillan, Maria: 1 article (01/2017)
5.	Martin-Guerrero, Idoia: 1 article (01/2017)
6.	Fitzgerald, Erin F: 1 article (12/2012)
7.	Huganir, Richard L: 1 article (12/2012)
8.	Hunganir, Richard L: 1 article (12/2012)
9.	Jensen, Frances E: 1 article (12/2012)
10.	Klein, Peter M: 1 article (12/2012)

Related Diseases

1.	Postoperative Pain 01/01/2011 - "Our study suggests that the therapeutic targeting the phosphorylation regulation of AMPA receptor GluR1 subunit at Serine-831 site would be potentially significant for treating postoperative pain."
2.	Hypersensitivity (Allergy) 01/01/2017 - "In this review we have summarized the results of those studies which describe the involvement of four different genes, being polymorphisms in the glutamate receptor, ionotropic, AMPA 1 (GRIA1) the most frequently associated with asparaginase hypersensitivity. "
3.	Seizures (Absence Seizure) 12/05/2012 - "We showed previously that hypoxia-induced seizures in a neonatal rat model induce rapid phosphorylation of serine-831 (S831) and Serine 845 (S845) sites of the AMPA receptor GluR1 subunit and later neuronal hyperexcitability and epilepsy, suggesting that seizure-induced posttranslational modifications may represent a novel therapeutic target. "
4.	Epilepsy (Aura) 12/05/2012 - "We showed previously that hypoxia-induced seizures in a neonatal rat model induce rapid phosphorylation of serine-831 (S831) and Serine 845 (S845) sites of the AMPA receptor GluR1 subunit and later neuronal hyperexcitability and epilepsy, suggesting that seizure-induced posttranslational modifications may represent a novel therapeutic target. "
5.	Hypoxia (Hypoxemia) 12/05/2012 - "We showed previously that hypoxia-induced seizures in a neonatal rat model induce rapid phosphorylation of serine-831 (S831) and Serine 845 (S845) sites of the AMPA receptor GluR1 subunit and later neuronal hyperexcitability and epilepsy, suggesting that seizure-induced posttranslational modifications may represent a novel therapeutic target. "

Related Drugs and Biologics

1.	Asparaginase (Elspar)
2.	Serine (L-Serine)