YM 511

07/01/2003 - "YM511 appeared to be effective and safe in postmenopausal patients with breast cancer. "
10/27/2016 - "A series of compounds was synthesized based on YM511, which has previously been used for breast cancer treatment. "
07/01/2003 - "Early phase II study of the new aromatase inhibitor YM511 in postmenopausal patients with breast cancer. "
09/01/2003 - "However, YM511 did not demonstrate anti-proliferative effects in hormone sensitive breast carcinomas. "
05/01/1996 - "Inhibitory effect of a novel non-steroidal aromatase inhibitor, YM511 on the proliferation of MCF-7 human breast cancer cell."

05/01/1996 - "YM511 may be useful in the treatment of estrogen-dependent cancers."
07/01/2003 - "A phase II study of a non-steroidal selective aromatase inhibitor, YM511, 4-[N-bromobenzyl]-N-(4H-1,2,4-triazol-4-yl)amino) benzonitrile, was conducted to evaluate the anti-tumor response, dose-dependence of response rate and tolerability in postmenopausal patients with advanced breast cancer. "

09/01/1997 - "Inhibitory effects of a novel aromatase inhibitor, YM511, on growth of endometrial explants and insulin-like growth factor-I gene expression in rats with experimental endometriosis."